| Parameter | Specification |
|---|---|
| Source | Non-GMO fermentation-derived / sustainable vegetable oils |
| CAS Number | 83-46-5 (β-Sitosterol) |
| Total Sterols | ≥99.0% (GC-FID) |
| Composition Profile | β-Sitosterol: 45–55%; Campesterol: 20–30%; Stigmasterol: 15–25% |
| Test Method | GC-FID (sterol profile), ICP-MS (heavy metals), Titration (purity) |
| Appearance | White to off-white crystalline powder |
| Packaging | 25 kg/drum with double food-grade polyethylene liners; smaller sizes available |
| Key Properties | Natural phytosterol complex, oil-soluble, stable crystalline form, non-GMO, vegan |
| Application | Dietary supplements, functional foods, heart health formulations, cosmetics, personal care |
Cardiovascular & Functional Health Powerhouse
SRBio Plant Sterols (Phytosterols) is a high-purity, naturally derived sterol complex produced through advanced non-GMO fermentation technology. As a clinically established ingredient for cardiovascular wellness, this phytosterol blend supports healthy cholesterol levels through a well-documented mechanism of action. SRBio’s proprietary fermentation and purification platform ensures exceptional purity, consistent composition, and formulation-ready performance for a wide range of dietary supplement, functional food, and personal care applications.
Uncompromising Quality: SRBio’s Manufacturing Excellence
1. Precision Purity & Composition Control
| Parameter | SRBio Standard | Industry Typical | Test Method |
|---|---|---|---|
| Total Sterols | ≥99.0% | 90.0% – 95.0% | GC-FID (AOAC 994.10) |
| β-Sitosterol | 45–55% | 40–50% | GC-FID (USP <1724>) |
| Campesterol | 20–30% | 20–30% | GC-FID |
| Stigmasterol | 15–25% | 15–25% | GC-FID |
| Free Cholesterol | ≤0.1% | 0.5% – 2.0% | Enzymatic Colorimetry |
| Heavy Metals (Total) | <10 ppm | ≤20 ppm | ICP-MS (USP <232>/<233>) |
| Lead (Pb) | <0.5 ppm | ≤1.0 ppm | ICP-MS |
| Arsenic (As) | <0.5 ppm | ≤1.0 ppm | ICP-MS |
| Cadmium (Cd) | <0.1 ppm | ≤0.5 ppm | ICP-MS |
| Mercury (Hg) | <0.05 ppm | ≤0.1 ppm | ICP-MS |
| Loss on Drying | ≤1.0% | ≤2.0% | Karl Fischer |
| Residue on Ignition | ≤0.2% | ≤0.5% | USP <281> |
| Peroxide Value | ≤1.0 meq/kg | ≤5.0 meq/kg | AOCS Cd 8b-90 |
| Residual Solvents | Class 1: ND; Class 2: <10 ppm | Variable | HS-GC-MS |
2. Advanced & Sustainable Production Technology
Proprietary Fermentation Platform
SRBio utilizes optimized non-GMO Saccharomyces cerevisiae strains for high-yield sterol production. This advanced fermentation approach ensures:
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Superior consistency: Independent of seasonal and geographic variability
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Non-animal origin: Suitable for vegan formulations
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Reduced environmental impact: Lower energy and water consumption compared to plant extraction
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High yield: Achieves sterol concentrations significantly above industry averages
Solvent-Free Extraction & Purification
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Supercritical CO₂ Fractionation: Environmentally friendly extraction at 300 bar and 60°C eliminates organic solvent residues
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Molecular Imprinting Chromatography: Proprietary technology removes free cholesterol to ≤0.1%, ensuring clean label compliance
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Controlled Crystallization: Optimized conditions yield uniform crystalline particles with consistent morphology
Precision Esterification Options
For enhanced formulation versatility, SRBio offers enzymatic esterification using immobilized lipase technology (≥98% conversion):
| Ester Type | Properties | Applications |
|---|---|---|
| Fatty Acid Esters (C8–C18) | Oil-soluble, emulsion-friendly | Softgels, functional spreads, lipid-based formulations |
| Glycosides | Water-soluble | Beverages, clear liquid supplements |
| Ferulic Acid Conjugates | Enhanced antioxidant properties | Cosmeceuticals, anti-aging formulations |
Superior Stability & Shelf-Life
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Long-Term Stability: Retains ≥98% potency after 48 months under ambient conditions (≤25°C, ≤60% RH) in sealed, light-protected packaging
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Oxidation Control: Low peroxide value (≤1.0 meq/kg) ensures minimal oxidation; nitrogen-flushed packaging with oxygen absorbers maintains stability
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Light Protection: Amber containers or foil packaging protect against UV-induced degradation
Scientific & Functional Overview for Nutritional & Cosmetic Applications
1. Cardiovascular Health Support
Cholesterol Management Mechanism
Plant sterols structurally resemble cholesterol and help maintain healthy cholesterol levels by competing with dietary and biliary cholesterol for absorption in the intestines. This mechanism, supported by extensive scientific research, contributes to cardiovascular wellness when used as part of a balanced diet.
Regulatory Recognition
The European Food Safety Authority (EFSA) has approved health claims linking plant sterols to the maintenance of normal blood cholesterol levels. SRBio provides full documentation to support regulatory submissions for health claims.
2. Formulation Synergies for Heart Health
Plant sterols are highly compatible with other cardiovascular wellness ingredients, enabling synergistic formulations:
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Omega-3 Fatty Acids: Complementary mechanisms for comprehensive cardiovascular support
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Red Yeast Rice: Combined approach for maintaining healthy lipid profiles
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Coenzyme Q10: Supports energy metabolism alongside cholesterol management
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Soluble Fiber: Enhanced cholesterol-lowering effects through dual mechanisms
3. Skin Barrier Function & Dermatological Benefits
Barrier Repair Support
Phytosterols help support and restore the skin’s natural barrier function by integrating into the lipid matrix of the stratum corneum. They work synergistically with ceramides to improve hydration and protect against environmental stressors.
Anti-Aging Properties
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Supports collagen health and skin elasticity
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Exhibits soothing properties beneficial for sensitive or mature skin
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Provides emollient effects without greasiness
Cosmetic Applications
Widely used in anti-aging creams, barrier repair moisturizers, and serums at concentrations typically ranging from 0.5% to 3.0%.
4. Metabolic & Immune Support
Plant sterols have been studied for their broader metabolic and immune-supporting properties, including:
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Insulin Sensitivity: May support healthy glucose metabolism
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Inflammatory Response: Contributes to normal inflammatory balance
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Cellular Health: Supports overall cellular function and vitality
Technical Specifications & Formulation-Ready Advantages
| Parameter | SRBio Plant Sterols Standard | Test Method |
|---|---|---|
| Appearance | White to off-white, free-flowing crystalline powder | Visual Inspection |
| Total Sterols | ≥99.0% | GC-FID |
| β-Sitosterol | 45–55% | GC-FID |
| Campesterol | 20–30% | GC-FID |
| Stigmasterol | 15–25% | GC-FID |
| Free Cholesterol | ≤0.1% | Enzymatic Colorimetry |
| Melting Point | 135–145°C | USP <741> |
| Loss on Drying | ≤1.0% | Karl Fischer |
| Residue on Ignition | ≤0.2% | USP <281> |
| Solubility | Soluble in oils, fats, and organic solvents; insoluble in water | USP <1236> |
| Bulk Density | 0.45 – 0.65 g/mL | USP <616> |
| Particle Size (D90) | ≤100 μm (customizable) | Laser Diffraction |
| Peroxide Value | ≤1.0 meq/kg | AOCS Cd 8b-90 |
| Heavy Metals (Total) | <10 ppm | ICP-MS |
| Total Aerobic Microbial Count | ≤100 CFU/g | USP <61> |
| Total Yeast & Mold Count | ≤50 CFU/g | USP <61> |
| E. coli / Salmonella | Negative /25g | USP <62> |
Formulation-Ready Benefits by Application:
| Application | Key Advantage |
|---|---|
| Dietary Supplements (Softgels) | Readily soluble in oil carriers; stable in gelatin or vegetarian softgel formulations. |
| Dietary Supplements (Capsules) | Excellent flowability for hard-shell capsules; compatible with other lipophilic ingredients. |
| Tablet Formulations | Can be incorporated into tablet blends with appropriate excipients for heart health products. |
| Functional Foods | Suitable for incorporation into spreads, margarines, dairy products, and fortified foods. |
| Functional Beverages | Water-soluble glycoside forms available for clear beverage applications. |
| Cosmetics & Personal Care | Easily incorporated into the oil phase of emulsions; stable in creams, lotions, and serums. |
Supply Chain & Compliance Leadership
1. Audited Transparency & Traceability
Full Traceability: Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing total sterols, composition profile, free cholesterol, heavy metals, microbiology, and physical properties. Complete fermentation and purification records are available for qualified client audits.
Rapid Sampling: 50 g or 500 g R&D samples shipped within 72 hours with full COA + MSDS.
2. Global Regulatory Certifications
| Certification / Compliance | Status |
|---|---|
| ISO 22000 & FSSC 22000 | Certified (all production sites) |
| Kosher & Halal | Certified |
| Non-GMO | Verified; fermentation strains and raw materials are non-GMO |
| Allergen-Free Statement | Gluten-free, soy-free, dairy-free, egg-free, peanut-free (ELISA tested) |
| Vegan | Fermentation-derived, no animal inputs |
| EFSA Health Claim Support | Documentation available for cholesterol reduction claims |
| FDA GRAS | Generally Recognized as Safe for food applications |
| USDA BioPreferred® | Certified |
| IPEC/GMP | Compliant for pharmaceutical excipient applications |
3. Supply Chain Resilience
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Global Capacity: 20 MT/month standard, expandable to 50 MT
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Inventory Buffer: 6-month safety stock maintained in EU, US, and APAC hubs
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Redundant Manufacturing: Multiple fermentation lines and purification trains ensure uninterrupted supply
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Blockchain Traceability: Batch-level tracking for full supply chain transparency
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Disruption Plan: Dual sourcing for all critical inputs
Competitive Breakdown: SRBio vs. Market Alternatives
| Capability | SRBio Plant Sterols | Standard Market Grade |
|---|---|---|
| Total Sterols | ≥99.0% | 90.0% – 95.0% |
| Free Cholesterol | ≤0.1% | 0.5% – 2.0% |
| Batch-to-Batch Consistency | ±1.0% total sterols variance | ±5.0% or higher |
| Heavy Metals | <10 ppm total | ≤20 ppm or higher |
| Peroxide Value | ≤1.0 meq/kg | ≤5.0 meq/kg, often higher |
| Residual Solvents | None detected | May contain hexane or ethanol residues |
| Particle Size Control | Customizable 0.1–50 μm | Limited, typically >100 μm |
| Oxidation Stability | 48 months real-time data | 24 months extrapolated |
| Documentation | Full COA, composition profile, regulatory dossiers | Limited or incomplete |
| Lead Time (1 MT) | 21 days | 60–90 days |
| Active Regulatory Dossiers | 14 global | ≤3 |
Technical Partnership Program
1. Co-Development Services
Formulation Support
Our applications lab can assist with:
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Solubility and compatibility studies in oil-based systems (softgels, emulsions)
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Stability testing in finished formulations (capsules, spreads, creams)
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Synergy studies with omega-3s, stanols, prebiotics, and other heart-health ingredients
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Bioavailability enhancement through nanoemulsions or cyclodextrin inclusion complexes
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Custom particle size for specific formulation requirements
Advanced Delivery Systems
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Nanoemulsions: High-shear homogenization achieving D90 <200 nm for enhanced bioavailability
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Liposomal Delivery: Improved absorption for cosmeceutical and supplement applications
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γ-Cyclodextrin Complexes: Enhanced water solubility for beverage applications
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Enteric Coatings: pH-triggered release for targeted intestinal delivery
Analytical Method Transfer
We provide validated GC-FID methods for accurate quantification of sterol profiles in finished products, enabling seamless integration into your quality management system.
2. Market-Ready Solutions
Custom Premixes for Heart Health
| Blend Name | Composition | Target Application |
|---|---|---|
| CardioBalance™ | Plant Sterols + Omega-3 (EPA/DHA) + CoQ10 | Cardiovascular wellness softgels |
| Cholesterol Support Complex | Plant Sterols + Red Yeast Rice + Bergamot | Heart health supplements |
| Fiber-Sterol Blend | Plant Sterols + Soluble Fiber (psyllium/beta-glucan) | Functional foods, powdered mixes |
| Metabolic Health Formula | Plant Sterols + Berberine + Chromium | Metabolic wellness formulations |
Custom Premixes for Skin Care
| Blend Name | Composition | Target Application |
|---|---|---|
| Barrier Repair Complex | Plant Sterols + Ceramides + Squalane | Moisturizers, barrier repair creams |
| Anti-Aging Serum Base | Plant Sterols + Vitamin E + CoQ10 | Anti-aging serums, night creams |
| Soothing Skin Blend | Plant Sterols + Oat Extract + Allantoin | Sensitive skin formulations |
Private Label Ready
Turnkey formulations available for:
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Softgels (500 mg, 1000 mg plant sterols)
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Hard-shell capsules (standardized sterol blends)
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Functional spreads and margarines
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Anti-aging creams and barrier repair moisturizers
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Powdered drink mixes for heart health
Sustainability Leadership
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Carbon Negative Process: -2.1 kg CO₂e per kg of product
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Zero Wastewater: Closed-loop water recovery system
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Renewable Energy: Manufacturing facilities powered by renewable sources
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USDA BioPreferred® Certified: Recognized for biobased content
Partner with SRBio for High-Purity, Formulation-Ready Plant Sterols
Ready to formulate with the industry’s most consistent, high-purity plant sterols? Request custom samples, technical dossiers, or discuss co-development opportunities for your next-generation heart health supplements, functional foods, or advanced skin care products.
→ Email: admin@plantextractssr.com
Shipping & Packing Information
OEM SERVICE
We offer all-inclusive product development from consultation to delivery.
We make product proposals based on the customer’s requirements, from small to large lots.
