Overview
Ergosterol, also known as provitamin D₂, is a core sterol component of fungal cell membranes and a critical precursor for vitamin D₂ production. SRBio Ergosterol is manufactured through advanced microbial fermentation and multi-stage purification, delivering ultra-high purity, exceptional stability, and full regulatory compliance. It supports immune health, skin integrity, liver function, and serves as a key intermediate for steroid hormone and pharmaceutical API production.
Product Specifications
| Parameter | Specification |
|---|---|
| Chemical Name | Ergosterol; Provitamin D₂ |
| CAS Number | 57-87-4 |
| Specification | ≥98.0% (HPLC) |
| Test Method | HPLC-UV, GC-FID, ICP-MS |
| Packaging | Double foil bags; 100g – 25kg |
| Key Benefits | Precursor to Vitamin D₂, immune regulation, skin barrier support, liver health, metabolic balance |
| Application | Dietary supplements, pharmaceutical intermediates, skincare formulas, feed additives, functional foods |
Uncompromising Quality: SRBio’s Manufacturing Excellence
1. Precision Quality Control
| Parameter | SRBio Standard | Competitor Average | Test Method |
|---|---|---|---|
| Ergosterol Purity (HPLC) | ≥98.0% | 95.0%–97.0% | HPLC-UV |
| Heavy Metals (Pb, As) | <0.1 ppm | ≤1.0 ppm | ICP-MS |
| Residual Solvents | ND | ≤500 ppm | GC-FID |
| Loss on Drying | ≤0.5% | ≤1.0% | Gravimetry |
| Microbial Limits | Total plate count <100 CFU/g; Pathogens negative | Standard USP limits | USP <61> & <62> |
2. Advanced Production Technology
- Controlled Microbial Fermentation: High-yield fungal strains ensure consistent output and natural origin.
- Solvent-Free Purification: Multi-stage recrystallization without harmful organic solvents for clean-label safety.
- Polymorph & Stability Control: Strict temperature and pressure control to maintain crystal integrity.
- Nitrogen-Flushed Packaging: Protects from oxidation, light, and moisture for long shelf life.
- Sustainable Production: Non-GMO, vegan-friendly, zero animal derivatives, low carbon footprint.
3. Stability & Shelf-Life Superiority
| Parameter | SRBio Ergosterol | Conventional Ergosterol |
|---|---|---|
| Stability (25°C / 60% RH) | ≥95% potency at 24 months | ~85% potency at 12 months |
| Light Resistance | Strong; protected formulation | Rapid degradation under light |
| pH Stability | Stable in pH 3.0–8.0 | Unstable in neutral/alkaline conditions |
| Storage | Cool, dry, dark place | Strict light-proof & low-humidity storage |
Scientific Evidence: Mechanism & Clinical Efficacy
1. Vitamin D₂ Precursor Activity
Mechanism: Ergosterol is converted to vitamin D₂ (ergocalciferol) under UV irradiation, supporting calcium absorption, bone mineralization, and musculoskeletal health.
Clinical Outcomes:
- Essential for maintaining normal bone density and preventing bone loss.
- Supports healthy immune function via vitamin D₂-mediated pathways.
2. Immune Modulation
Mechanism: Regulates innate and adaptive immune responses by supporting membrane integrity and cell signaling.
Clinical Outcomes:
- Promotes balanced inflammatory response.
- Supports respiratory and systemic immune resilience.
3. Skin Health & Barrier Repair
Mechanism: Reinforces lipid bilayer structure, reduces transepidermal water loss (TEWL), and supports skin cell renewal.
Clinical Outcomes:
- Improves skin hydration, elasticity, and smoothness.
- Protects against environmental stress and oxidative damage.
4. Liver & Metabolic Support
Mechanism: Supports liver cell membrane stability and promotes healthy lipid metabolism.
Clinical Outcomes:
- Aids liver tissue repair and normal detoxification function.
- Helps maintain healthy cholesterol and lipid profiles.
5. Antifungal & Pharmaceutical Value
Mechanism: Critical structural component of fungal cell membranes, making it a key target for antifungal drug development.
Application Value:
- Core intermediate for vitamin D₂, cortisone, and steroid hormone APIs.
- Used in anti-trypanosomal and antifungal drug research and production.
Formulation-Ready Advantages
| Property | SRBio Ergosterol | Competitor Average |
|---|---|---|
| Format | Free-flowing crystalline powder | Crystalline powder |
| Purity Consistency | ≥98.0% batch-to-batch | Variable |
| Organoleptic | Neutral taste & odor | Noticeable characteristic odor |
| Solubility | Good solubility in lipid matrices; dispersible in formulations | Poor aqueous solubility |
| Flowability | Excellent for tableting & encapsulation | Poor |
| Stability | 24-month shelf life | 12-month typical |
Application-Specific Benefits
- Dietary Supplements: Ideal for capsules, tablets, softgels; supports bone, immune, and daily wellness formulas.
- Pharmaceutical Manufacturing: GMP-grade precursor for vitamin D₂ and steroid API production.
- Skincare Products: Compatible with creams, serums, and lotions for barrier repair and anti-aging.
- Functional Foods & Beverages: Suitable for fortified powders, bars, and lipid-based drinks.
- Animal Nutrition: Feed additive to support skeletal health and vitamin D synthesis.
Supply Chain & Compliance Leadership
1. Audited Transparency & Traceability
- Blockchain Traceability: Batch-specific COA and production records accessible via QR code.
- Dual-Sourcing Strategy: ISO 22000 / HACCP certified facilities in China and EU.
- Global Stock Hubs: Pre-positioned inventory in US, EU, and Asia for fast fulfillment.
2. Global Regulatory Certifications
| Certification / Compliance | Status |
|---|---|
| cGMP (FDA-registered facility) | Fully compliant |
| ISO 22000 / HACCP | Certified |
| Halal & Kosher | Certified |
| Vegan & Non-GMO | Verified |
| Allergen-Free | Soy-free, gluten-free, dairy-free |
| USP/NF/FCC Grade | Compliant |
3. Supply Chain Resilience
- Redundant production lines and multi-region warehouses minimize supply risks.
- Samples shipped within 48 hours; bulk orders with expedited logistics available.
Competitive Breakdown: SRBio vs. Market Alternatives
| Capability | SRBio Ergosterol | Generic Ergosterol |
|---|---|---|
| Purity | ≥98.0% | 95.0%–97.0% |
| Stability | 24-month shelf life | 12-month typical |
| Heavy Metals | <0.1 ppm | ≤1.0 ppm |
| Residual Solvents | ND | Often detectable |
| Production | Fermentation-based, solvent-free | Chemical synthesis with solvents |
| Certifications | Full global compliance | Limited |
| Formulation Flexibility | High | Moderate |
Partner Success Stories
European Pharmaceutical API Manufacturer
“SRBio Ergosterol delivers consistent ≥98% purity and full regulatory documentation, which streamlined our vitamin D₂ production process. The stability and supply reliability have greatly reduced our production risks.”
— Head of R&D
US Skincare Brand
“We use SRBio Ergosterol in our barrier-repair serum line. Its excellent compatibility and skin-friendly profile make it a star ingredient for sensitive and dry skin formulas.”
— Product Development Director
Technical Partnership Program
1. Co-Development Services
- Stability Studies: ICH-guided testing for capsules, creams, beverages, and pharma blends.
- Custom Grades: Tailored purity and particle size for pharmaceutical, cosmetic, or feed use.
- Bioavailability & Safety Testing: Full analytical support for regulatory filings.
2. Market-Ready Solutions
- Private Label Kits: Turnkey capsules, tablets, and softgels with full dossiers.
- Custom Packaging: Nitrogen-flushed foil bags, drums with desiccants, branded options.
- Regulatory Support: Complete documentation for GRAS, Novel Food, and local health authority submissions.
3. Rapid Sampling
Receive 50g–100g trial samples with full COA, stability data, and MSDS within 72 hours.
Partner with SRBio
Secure your supply of high-purity, stable, and fully compliant Ergosterol for pharmaceuticals, nutraceuticals, skincare, and animal nutrition. Request samples, technical dossiers, or custom formulation support today.
Email: admin@plantextractssr.com
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OEM SERVICE
We offer all-inclusive product development from consultation to delivery.
We make product proposals based on the customer’s requirements, from small to large lots.
