4-Butylresorcinol Powder Manufacturer & Supplier
CAS No.: 18979-61-8
Molecular Formula: C10H14O2
Purity: ≥99.0% (HPLC)
Grade: Cosmetic Grade (High-Potency Whitening Agent)
1. Product Overview
4-Butylresorcinol is a revolutionary skin-lightening organic compound that has set a new standard in the treatment of hyperpigmentation. Unlike traditional brighteners, 4-Butylresorcinol acts as a strong inhibitor of both tyrosinase and peroxidase, the two primary enzymes responsible for melanin production.
At Xi’an SR Bio-Engineering, our 4-Butylresorcinol is produced through a proprietary purification process, resulting in a high-purity crystalline powder with minimal odor and excellent compatibility. It is the premier choice for professional-grade “spot-correctors” and intensive whitening formulations.
2. Technical Comparison: Why It Leads the Market
In the competitive landscape of skin-lightening ingredients, 4-Butylresorcinol demonstrates superior technical performance:
| Ingredient | Tyrosinase Inhibition (IC50) | Stability | Safety Profile |
| Kojic Acid | Moderate | Low (Easy to discolor) | Irritation risk |
| Arbutin | Low | Moderate | Safe |
| 4-Butylresorcinol | Extremely High | High (Optimized) | Excellent / Non-toxic |
| Hydroquinone | High | Low | High Risk (Regulated) |
3. Deep-Dive: Mechanism of Action
How 4-Butylresorcinol works at the cellular level:
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Enzyme Inhibition: It binds directly to the active site of Tyrosinase, preventing the conversion of L-DOPA to Eumelanin.
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TRP-1 Inhibition: It specifically targets Tyrosinase-Related Protein 1 (TRP-1), which stabilizes the melanogenic enzymes.
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DNA Modulation: Recent studies suggest it can influence the expression of melanogenic genes, providing a long-term brightening effect rather than just temporary surface fading.
4. Formulation Guidelines (For R&D Teams)
We provide technical support to ensure the stability of 4-Butylresorcinol in your finished products:
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Recommended Dosage: 0.1% – 0.5% (Max 2.0% for intensive spot treatments).
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Optimal pH Range: Stable between pH 4.5 – 6.0.
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Solubility: Highly soluble in alcohol, propylene glycol, and most cosmetic oils. Insoluble in water (requires pre-dissolving in oil phase or solvents).
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Processing: Should be added during the cooling phase (below $50^{\circ}\text{C}$) to maintain maximum potency.
5. End-to-End OEM and ODM Partnership
Maximize the efficacy of 4-Butylresorcinol with our turnkey manufacturing solutions:
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Synergistic Whitening Systems: We specialize in blending 4-Butylresorcinol with Hexylresorcinol, Niacinamide, and VC Derivatives to create multi-pathway whitening effects.
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Advanced Delivery Systems:
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Liposomal Encapsulation: Enhancing skin penetration and reducing potential irritation.
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Anhydrous Serums: Maximizing the shelf-life of resorcinol-based products.
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Private Label Services: From medical-grade spot creams to luxury brightening essences, we handle formulation, stability testing, and final packaging.
6. Technical Specifications (COA)
| Test Item | Specification Standard | Actual Result |
| Appearance | Off-white to light yellow powder | Conforms |
| Assay (HPLC) | ≥ 99.0% | 99.62% |
| Melting Point | 52℃-55℃ | 53℃ |
| Loss on Drying | ≤ 0.5% | 0.18% |
| Total Heavy Metals | ≤ 10 ppm | < 2 ppm |
| Arsenic (As) | ≤ 2 ppm | < 1 ppm |
| Residue on Ignition | ≤ 0.1% | 0.04% |
7. Packaging & Global Logistics
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Standard Packing: 1kg/Aluminum Foil Bag (Vacuum sealed); 25kg/Fiber Drum.
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MOQ: 1kg (Supporting boutique brands and R&D pilot projects).
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Storage: Store in a cool, dry place (2-8℃}$ recommended for long-term bulk storage). Keep away from strong light.
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Lead Time: Ready-to-ship inventory with global delivery via FedEx, DHL, or Sea Freight.
Shipping & Packing Information
OEM SERVICE
We offer all-inclusive product development from consultation to delivery.
We make product proposals based on the customer’s requirements, from small to large lots.
