Sesamin

Sesamin

(Powder, Tablets and Capsules)

Basic Product Information

Parameter Details
Botanical Source Sesamum indicum L. (Sesame)
CAS Number 607-80-7
Molecular Formula C₂₀H₁₈O₆
Molecular Weight 354.36 g/mol
Active Ingredient Sesamin
Appearance White to off-white crystalline powder
Specification 10%–98% (HPLC)
Test Method HPLC (for sesamin content); GC-MS (for residual solvents)
Loss on Drying ≤1.0%
Heavy Metals Pb <0.1 ppm, As <0.05 ppm (exceeds USP/EP standards)
Residual Solvents None detected (GC-MS tested)
Melting Point 122–124°C
Particle Size 200-micron (adjustable)
Packaging 1 kg/bag (foil), 25 kg/drum, or customized packaging
MOQ 1 kg (flexible for R&D and commercial orders)
Storage Store at 15–25°C in a dry, well-closed container protected from light; long-term storage at –20°C recommended
Shelf Life 36 months under proper storage

Premium Sesamin by SRBio – High-Purity Lignan from Sesame Seed

SRBio Sesamin is a high-purity natural lignan extracted from the seeds of Sesamum indicum (sesame), one of the richest known sources of this bioactive compound. Sesamin is a furofuran lignan, a unique class of phytochemicals found almost exclusively in sesame seeds and sesame oil, where it serves as a key contributor to the oil‘s remarkable oxidative stability. The sesamin content in raw sesame seeds is naturally low—typically 0.5%–1.2%—making advanced extraction and purification technologies essential for producing high-purity sesamin isolates.

Produced using patented CO₂ supercritical extraction technology followed by precision chromatography, SRBio Sesamin achieves industry-leading purity of 98%–99.5% (HPLC-verified), significantly exceeding the typical industry standard of 90%–95%. This solvent-free, green extraction process preserves the molecular integrity of sesamin while eliminating toxic solvent residues. The result is a clean, high-purity product ideal for premium nutraceutical, functional food, and cosmeceutical formulations.

Sesamin has been the subject of extensive scientific research over the past three decades. Studies have demonstrated its potent antioxidant activity, ability to modulate fatty acid metabolism, vitamin E-sparing effects, and support for healthy liver function. As one of the most thoroughly studied sesame lignans, SRBio Sesamin offers manufacturers a science-backed ingredient with proven stability and consistent quality across every batch.

Manufacturing & Quality Excellence

  • Raw material sourcing: Ethically-sourced Sesamum indicum seeds from Xinjiang, China, selected for high sesamin content and grown under non-GMO, pesticide-free conditions. DNA authentication ensures no adulteration with S. alatum or other species.

  • Patented extraction technology: CO₂ supercritical extraction combined with multi-stage chromatography yields 98%+ sesamin purity without the use of toxic organic solvents. This green technology preserves the natural molecular structure of sesamin while eliminating solvent residue concerns.

  • Customizable specifications: Available in multiple potency grades ranging from 10% to 98% sesamin content, allowing manufacturers to select the ideal concentration for their specific formulation needs and cost targets.

  • Quality testing: Each batch undergoes rigorous quality control including HPLC assay for sesamin content, chiral purity testing to exclude inactive isomers, ICP-MS heavy metal screening (Pb <0.1 ppm, As <0.05 ppm), GC-MS residual solvent analysis (none detected), and microbial testing (TPC <100 CFU/g, zero pathogens).

  • Certifications: Our facility complies with cGMP, ISO 22000, FSSC 22000, and HACCP standards. FDA Drug Master File (DMF) on file. Kosher, Halal, and Non-GMO certifications available upon request. Allergen statement and GMO-free declaration provided with each shipment.

Core Product Advantages

  1. Industry-leading purity — 98% sesamin content (HPLC-verified), significantly exceeding the industry average of 90%–95%. Impurities such as sesamolin and sesaminol are controlled below 0.5%.

  2. Superior antioxidant activity — Sesamin is a potent scavenger of free radicals (ROS and RNS), mitigating oxidative stress by donating electrons to reactive species and preventing cellular damage and lipid peroxidation. It also upregulates endogenous antioxidant enzymes including SOD, catalase, and GSH-Px.

  3. Vitamin E-sparing effect — Sesamin inhibits vitamin E metabolism, resulting in increased circulating levels of γ-tocopherol and γ-tocotrienol. Oral ingestion of 100–150 mg of sesamin is sufficient to preserve vitamin E levels in the body, making it a valuable co-ingredient in antioxidant formulations.

  4. Metabolic support — Research indicates sesamin modulates fatty acid metabolism and inhibits cholesterol absorption and biosynthesis, supporting healthy lipid profiles and liver function in connection with alcohol metabolism.

  5. Low MOQ with flexible options — Minimum order quantity starts at just 1 kg, ideal for R&D projects, clinical trials, and small-batch production. Annual production capacity of 5,000 kg (expandable to 15,000 kg) supports seamless scaling from laboratory to commercial volumes.

  6. Patented green extraction — CO₂ supercritical extraction + chromatography delivers 99.5% purity without toxic solvents, ensuring a clean, sustainable, and structurally intact product.

  7. End-to-end traceability — Blockchain-tracked transparency with QR code access to seed origin (farm GPS coordinates), extraction batch logs, and third-party lab reports from Eurofins/SGS.

  8. Excellent formulation compatibility — Available as white crystalline powder (adjustable mesh size up to 200-micron) compatible with capsules, tablets, oil suspensions, water-dispersible powders, and complex blends with other nutraceuticals.

Physical & Formulation Properties

Property Value / Description
Appearance White to off-white crystalline powder
Odor Characteristic, neutral
Purity (HPLC) 98%
Melting point 122–124°C
Specific rotation [α]²⁰/D +65.0 to +69.0 deg (C=1, CHCl₃)
Solubility Fat-soluble; soluble in oils, DMSO (>70 mg/mL), and chloroform; practically insoluble in water and ethanol
Bulk density 0.4–0.6 g/mL
Particle size 200-micron (adjustable to customer requirements)
Hygroscopicity Low — stable under normal humidity
Flowability Good — suitable for encapsulation and tableting
Residual solvents None detected (GC-MS)
Stability 36 months at 15–25°C (accelerated stability data available)

Application Benefits

  • Dietary supplements
    Sesamin is widely used in liver health formulations (200–400 mg/day, often synergized with milk thistle), weight management products (300 mg sesamin + 100 mg CLA supported by clinical data on fat oxidation), and antioxidant blends (2%–5% inclusion in premium multivitamins).

  • Functional foods & beverages
    The clean, neutral taste profile allows seamless integration into functional food matrices. Oil suspensions (10%–50% sesamin) and water-dispersible powder formats are available for beverages, nutrition bars, and ready-to-mix drink powders.

  • Cosmeceuticals
    Sesamin is valued in topical formulations for its UV-protective properties (inhibits MMP-1 collagenase) and anti-aging benefits (upregulates Nrf2 pathway). Suitable for serums, anti-aging creams, and sun protection products.

  • Animal nutrition
    In aquaculture feed, 0.1% sesamin inclusion has been shown to enhance shrimp survival rates by 15%. For dairy cattle, sesamin supplementation reduces somatic cell count in milk.

  • Sports nutrition
    Emerging research positions sesamin as a supportive ingredient for fat oxidation and metabolic efficiency, making it attractive for weight management and sports performance products.

Supply Chain & Compliance

  • Production capacity: 5,000 kg per year (expandable to 15,000 kg) to meet growing market demand.

  • MOQ flexibility: From 1 kg (R&D and small-batch production) to metric ton contracts.

  • Lead time: 7–10 days for stock quantities; 15–20 days for custom specifications.

  • Documentation support: COA, MSDS, allergen statement, GMO‑free declaration, and specification sheet provided with each shipment.

  • Regulatory compliance: Pre-compiled dossiers available for FDA NDIs/GRAS, EFSA Novel Food, Health Canada NHP, and TGA compliance.

  • Third‑party testing: Available upon request for heavy metals, residual solvents, chiral purity, and stability studies.

Technical Support & Custom Solutions

SRBio offers comprehensive technical support to ensure seamless integration of sesamin into your formulations:

  • Custom potency grades: Available from 10% to 98% sesamin content, allowing precise cost and efficacy optimization.

  • Specialized formats: Oil suspensions (10%–50% sesamin), water-dispersible powder, or custom blends with complementary ingredients such as tocopherols.

  • Custom particle size: Mesh size adjustable up to 200-micron to suit specific tableting or encapsulation requirements.

  • Premix blends: Pre‑mixed with vitamin E, milk thistle extract, or other nutraceuticals to streamline your production process.

  • Packaging options: Nitrogen-flushed foil bags (1 kg, 5 kg), amber glass bottles, or custom-labeled drums with moisture-barrier protection.

  • Regulatory support: Pre-compiled technical dossiers for global product registrations (FDA, EFSA, Health Canada, TGA).

Why Choose SRBio Sesamin?

  • Cost-effective alternative to Japanese suppliers: Vertical integration from farm partnerships to in-house extraction delivers exceptional value—40% lower MOQ compared to Japanese suppliers, with bulk pricing incentives available.

  • Consistent quality guarantee: Each batch consistently exceeds 98.5% purity (HPLC-verified), with zero batch failures reported by long-term clients. Chiral purity testing ensures only the active isomer is present.

  • Patented technology advantage: CO₂ supercritical extraction + chromatography yields 99.5% purity without toxic solvents—a significant advancement over conventional extraction methods.

  • End-to-end traceability: Blockchain transparency with QR code access to complete supply chain data, from seed origin to third-party lab reports.

  • Customer‑centric service: Minimum order quantity starts at just 1 kg, making SRBio Sesamin accessible to R&D teams, startups, and established brands alike.

  • Global logistics: Reliable shipping to North America, Europe, Asia, Australia, and the Middle East, with on-time delivery guarantee.

Contact & Order Information

Ready to enhance your formulation with SRBio Sesamin? Request a free sample, COA, or quotation today.

For immediate assistance, please use the contact form on our website. We typically respond within 24 hours.

Video & Articles

Xi’an SR Bio-Engineering Co., Ltd

Xi’an SRBio is a professional wholesale provider of many quality nutritional supplements products and  AMINO ACID Powde etc.

We supply powder, tablets and capsules.

Shipping & Packing Information

Shipping & Packing Information

OEM SERVICE

We offer all-inclusive product development from consultation to delivery.
We make product proposals based on the customer’s requirements, from small to large lots.

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