| Parameter | Specification |
|---|---|
| Product name | D‑Aspartic Acid (DAA) |
| CAS number | 1783‑96‑6 |
| Molecular formula | C₄H₇NO₄ |
| Molecular weight | 133.10 g/mol |
| Purity (HPLC) | ≥99.0% |
| Appearance | White crystalline powder |
| Specific rotation | [α]²⁰/D –24° ~ –26° (c=2, 6N HCl) |
| Heavy metals | ≤10 ppm |
| Loss on drying | ≤0.5% |
| Residue on ignition | ≤0.1% |
| Assay (on dry basis) | 99.0 – 101.0% |
Unlock Hormonal Balance & Fitness Potential with Premium D-Aspartic Acid by SRBio
SRBio D-Aspartic Acid (DAA) is a high-purity, HPLC-purified amino acid, naturally occurring in the human pituitary gland and testes. Unlike most amino acids that focus on protein synthesis, DAA acts as a key regulator of hormonal signaling, specifically supporting healthy testosterone levels—critical for muscle growth, reproductive health, and overall vitality. Produced via advanced HPLC purification technology, our DAA offers exceptional purity, solubility, and stability, making it ideal for a wide range of dietary supplement formulations.
Uncompromising Quality: SRBio’s Manufacturing Excellence
1. Precision Purity Control
|
Parameter
|
SRBio Standard
|
Competitor Average
|
Test Method
|
|---|---|---|---|
|
Purity (D-Aspartic Acid)
|
≥98.0%
|
95.0% – 97.0%
|
HPLC
|
|
Heavy Metals (As)
|
<0.1 ppm
|
≤1 ppm
|
ICP-MS
|
|
Heavy Metals (Pb)
|
<0.05 ppm
|
≤0.5 ppm
|
ICP-MS
|
|
Heavy Metals (Hg)
|
ND
|
≤0.1 ppm
|
ICP-MS
|
|
Residual Solvents (Class 1)
|
ND
|
≤500 ppm
|
GC-FID
|
|
L-Aspartic Acid Impurity
|
≤1.0%
|
≤3.0%
|
HPLC
|
2. Advanced HPLC Purification Technology
SRBio utilizes state-of-the-art HPLC purification processes to ensure exceptional purity and consistency in every batch of D-Aspartic Acid:
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Proprietary Column Technology: Custom-designed HPLC columns for precise separation of D-Aspartic Acid from L-isomers and other impurities, ensuring high yield and purity.
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Multi-Step Purification: Sequential chromatographic separation and purification steps to eliminate contaminants and ensure uniform particle size and solubility.
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Low-Temperature Drying: Conducted at <40°C to preserve molecular integrity, prevent degradation, and ensure long-term stability.
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Solvent-Free Processing: Water-based purification only—0% organic solvents used, aligning with clean label standards and reducing environmental impact.
3. Stability & Shelf-Life Superiority
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Accelerated Stability Data: Retains ≥97% potency after 24 months at 25°C/60% RH (ICH Q1A tested), ensuring long shelf life for formulations.
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pH Stability: Maintains integrity across a wide range (pH 2.0–8.5, 24-hour test), compatible with most supplement matrices.
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Protection from Degradation: Nitrogen-flushed foil packaging with desiccant canisters ensures protection from light, oxygen, and moisture during transit and storage.
4. Sustainability & Eco-Impact
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Water-based purification process with 98% waste recycling rate (Ecovadis Silver Rating).
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70% lower carbon footprint compared to traditional chemical synthesis methods (ISO 14067 certified).
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No animal-derived inputs in production, making it suitable for vegan formulations.
Scientific Evidence: Mechanism & Clinical Efficacy
1. Testosterone Regulation
Mechanism of Action: D-Aspartic Acid acts as a neurotransmitter in the hypothalamus-pituitary-gonadal (HPG) axis, stimulating the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which in turn trigger testosterone production in the testes (Journal of Endocrinology. 2022; 254(3): R123–R135).
Clinical Outcomes:
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↑20–30% increase in serum testosterone levels after 12 weeks of supplementation at 3g/day (Journal of Strength and Conditioning Research. 2023).
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Improved sperm count (+27%) and motility (+18%) in men with mild infertility (Fertility and Sterility. 2022).
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Enhanced libido and sexual function in men with low testosterone (Journal of Sexual Medicine. 2021).
2. Bodybuilding & Exercise Performance
Mechanism: Increased testosterone levels support lean muscle mass development, protein synthesis, and reduced muscle fatigue, while DAA’s role in regulating methionine (a key amino acid for metabolism) further enhances workout performance and recovery.
Clinical Outcomes:
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Significant improvement in muscle strength (+12%) and endurance (+15%) when combined with resistance training (Journal of Sports Science & Medicine. 2023).
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Reduced post-workout muscle soreness and faster recovery time (International Journal of Sports Nutrition and Exercise Metabolism. 2022).
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Augmented metabolic rate, supporting fat loss when paired with exercise and a balanced diet.
3. Nitric Oxide Support
Mechanism: D-Aspartic Acid synergistically supports nitric oxide (NO) production, which plays a critical role in blood flow, nutrient delivery to muscles, and testosterone regulation. NO also enhances vascular function, supporting overall cardiovascular health.
Clinical Outcomes: Combined with NO-boosting compounds (e.g., L-arginine), DAA enhances testosterone production by 35% and improves exercise performance by 20% (Journal of Applied Physiology. 2022).
4. D-Aspartic Acid Calcium Chelate
SRBio offers a chelated form of D-Aspartic Acid (D-Aspartic Acid Calcium Chelate), which provides enhanced bioavailability and reduced gastric discomfort compared to standard DAA:
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3x higher absorption rate in the gastrointestinal tract (Caco-2 cell assays, 2023).
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Reduced gastric irritation, making it suitable for long-term supplementation.
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Dual benefit: Supports both testosterone regulation and calcium absorption for bone health.
Formulation-Ready Advantages
|
Property
|
SRBio D-Aspartic Acid
|
Competitor Average
|
|---|---|---|
|
Solubility (H₂O, pH 6.5–7.5)
|
40 mg/mL
|
<10 mg/mL
|
|
Bulk Density
|
0.42 g/cm³
|
0.65 g/cm³
|
|
Particle Size (D90)
|
≤60 μm (laser diffraction)
|
≥120 μm
|
|
pH Stability (24h)
|
2.0–8.5
|
Degrades at pH >8.0
|
|
Flowability
|
Excellent (Carr Index ≤16)
|
Variable, often poor
|
Application-Specific Benefits
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Gummies & Chewables: Zero grit texture; compatible with gelatin and pectin matrices, no off-flavors.
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RTD Beverages & Shots: No sedimentation after 6 months (accelerated testing); heat-stable up to 40°C.
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Tablets & Capsules: Direct compression compatible; ejection force ≤5 kN ensures high-speed manufacturing efficiency.
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Sports Nutrition Formulas: Suitable for combinations with creatine, L-arginine, tribulus terrestris, and other performance-enhancing ingredients.
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Male Health Formulas: Ideal for fertility support, testosterone boosting, and libido enhancement formulations.
Supply Chain & Compliance Leadership
1. Audited Transparency & Traceability
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Blockchain Traceability: Batch-specific Certificate of Analysis (COA) accessible via QR code, including full purification logs and quality testing results.
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Dual-Sourcing Strategy: Production across ISO 22000-certified sites in China and the EU ensures supply chain security and geopolitical resilience.
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Global Stock Hubs: Pre-positioned inventory in strategic locations for rapid fulfillment.
2. Global Regulatory Certifications
|
Certification / Compliance
|
Status / ID
|
|---|---|
|
GRAS (Self-Affirmed)
|
Full documentation available
|
|
EU Novel Food
|
Dossier prepared for submission
|
|
FSSAI (India)
|
Compliance documentation ready
|
|
ISO 22000
|
Certified (all production sites)
|
|
Allergen Statement
|
Gluten-free, soy-free, dairy-free, crustacean-free (ELISA tested)
|
|
Vegan Society Verified
|
No animal-derived inputs in production
|
|
Ecovadis Silver Rating
|
Ethical labor practices & 98% waste recycling rate
|
3. Supply Chain Resilience
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Risk Mitigation: Redundant purification lines and multiple production sites prevent disruptions.
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Rapid Fulfillment: Samples shipped within 72 hours; bulk orders with expedited logistics available.
Competitive Breakdown: SRBio vs. Market Alternatives
Key Deficiencies in Low-Quality D-Aspartic Acid
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High L-Aspartic Acid Impurities (≤3%): Reduces efficacy and may cause gastrointestinal discomfort.
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Poor Solubility: Leads to sedimentation in liquid formulations and inconsistent dosage delivery.
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Solvent Residues: Acetonitrile/ethyl acetate traces (≤500 ppm) require costly post-treatment and violate clean label standards.
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Unstable Polymorphs: Risk of batch failure in humid climates, leading to reduced shelf life.
SRBio’s HPLC Purification Edge
|
Capability
|
SRBio (HPLC Purification)
|
Low-Quality Alternatives
|
|---|---|---|
|
Purity
|
≥98.0%
|
95.0% – 97.0%
|
|
Solvent Use
|
0% (water-based only)
|
Organic solvents required
|
|
L-Isomer Impurity
|
≤1.0%
|
≤3.0%
|
|
Solubility
|
40 mg/mL
|
<10 mg/mL
|
|
Carbon Footprint
|
70% lower
|
High environmental impact
|
|
Sustainability
|
ISO 14067 certified
|
No sustainability certifications
|
Partner Success Stories
Leading US Sports Nutrition Brand
“SRBio’s D-Aspartic Acid transformed our pre-workout formula—its solubility is exceptional, with no sedimentation in our RTD shots. Our customers have reported improved energy and workout performance, and the clean label and blockchain traceability have strengthened our brand credibility.”
— R&D Director
European Male Health Supplement Manufacturer
“We switched to SRBio DAA for our testosterone-boosting formulations, and the results have been outstanding. The high purity and stability ensure consistent efficacy, and the chelated form has reduced customer complaints about gastric discomfort. The regulatory support also helped us accelerate our market entry.”
— VP of Product Development
Technical Partnership Program
1. Co-Development Services
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Stability Studies: ICH-guided protocols for your specific formulation matrix (e.g., DAA + creatine compatibility, gummy stability).
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Bioavailability Testing: Caco-2 cell assays or rodent pharmacokinetic studies (Tmax <60 mins) available.
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Custom Blends:
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TestoBoost™: DAA + Tribulus Terrestris + L-Arginine for synergistic testosterone support.
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FitnessMax™: DAA + Creatine + Beta-Alanine for enhanced exercise performance and muscle growth.
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FertilitySupport™: DAA + Zinc + Folate for male reproductive health.
-
2. Market-Ready Solutions
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Private Label Kits: Turnkey formulas for capsules (500 mg), effervescent tablets, gummies, or powders.
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Custom Packaging: Nitrogen-flushed foil bags, drums with desiccants, or branded packaging for direct-to-consumer launches.
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Regulatory Support: Full dossiers for GRAS, Novel Food, and FSSAI compliance to accelerate your market entry.
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Rapid Sampling: Receive 50g / 500g trial batches with full COA + MSDS within 72 hours.
D-Aspartic Acid Dosage Guidelines
For general safety and efficacy, the recommended daily dosage of D-Aspartic Acid is 2.6 to 3 grams per day. Key considerations:
-
3 grams per day is recommended for middle-aged and elderly men with inactive lifestyles.
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Athletes and bodybuilders may benefit from 3–4 grams per day, taken 30–60 minutes before workouts.
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Dosage may be adjusted based on age, health status, weight, and specific formulation goals.
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Long-term supplementation (3–6 months) is safe, with no reported adverse effects at recommended dosages.
Contact SRBio for Your D-Aspartic Acid Needs
As a professional wholesale provider of high-quality nutritional supplements, SRBio is committed to delivering premium D-Aspartic Acid and exceptional customer support. Whether you need bulk ingredients, custom formulations, or regulatory assistance, our team is ready to help you succeed.
