AKG

Product Overview

Alpha-Ketoglutarate (AKG) is a pivotal biological molecule that sits at the intersection of carbon and nitrogen metabolism. As a key intermediate in the Tricarboxylic Acid (TCA) cycle—also known as the Krebs Cycle—AKG is essential for the production of cellular energy (ATP) and serves as a primary precursor for the synthesis of critical amino acids like Glutamine and Arginine.

SRBio Alpha-Ketoglutarate is produced via high-precision synthesis, resulting in a crystalline powder with ≥99% purity. It is a cornerstone ingredient for manufacturers targeting the “Cellular Longevity,” “Metabolic Health,” and “Sports Performance” markets, providing a clean-label molecular foundation for high-performance products.

Technical Specifications

Key Advantages

1. Optimization of the Krebs Cycle

AKG acts as a crucial rate-limiting step in mitochondrial energy production. By providing a direct source of this intermediate, SRBio AKG supports the body’s natural ability to regenerate ATP, promoting sustained cellular vitality and metabolic efficiency.

2. Nitrogen Scavenging and Amino Acid Synthesis

AKG plays a fundamental role in the “transamination” process, helping to manage nitrogen balance by converting ammonia into L-Glutamine. This support for the nitrogen cycle is essential for maintaining healthy protein metabolism and protecting structural tissues during periods of metabolic stress.

3. Support for Collagen Structural Integrity

Emerging research highlights AKG’s role as a necessary cofactor for the enzyme prolyl 4-hydroxylase, which is vital for the formation of stable collagen fibers. This makes AKG an innovative ingredient for formulations targeting skin elasticity and connective tissue integrity.

Manufacturing Excellence

Advanced Molecular Purification

We utilize a highly controlled synthesis and multi-stage recrystallization process to ensure maximum purity. This results in an ultra-low impurity profile, free from residual fermentation by-products or harsh chemical catalysts, ensuring consistent behavior in your manufacturing environment.

Quality & Safety Compliance

• Molecular Identity: Every batch is verified via HPLC and FTIR to ensure precise molecular structure and potency.

• Purity Standards: Fully compliant with USP <232> and global safety regulations for elemental impurities.

• Clean Label: 100% Vegan, Non-GMO, and free from common allergens; suitable for high-end “clean-label” formulations.

Applications

SRBio Alpha-Ketoglutarate is engineered for leading-edge global brands:

• Metabolic & Longevity Stacks: A core ingredient for “Cellular Energy” capsules and products focusing on metabolic health.

• Advanced Sports Nutrition: Used to support the nitrogen cycle and recovery in high-performance pre-workout and post-workout blends.

• Skin & Connective Tissue Formulas: Pairs with Vitamin C and Amino Acids to support the natural integrity of the collagen matrix.

• Functional Beverages: Highly soluble and stable, making it ideal for concentrated wellness shots and dry drink mixes.

Technical Partnership Program

Custom Solutions & Formulation Support

• Mineral Derivatives: We also supply specialized salts, including Calcium AKG (Ca-AKG) and Arginine AKG (AAKG), for specific bioavailability requirements.

• Synergistic Blends: Expertise in formulating AKG with SRBio PQQ, CoQ10, or Liposomal B-Vitamins.

• Regulatory Dossiers: Immediate access to COA, MSDS, and comprehensive stability data for global product registration.

Request a Sample

Empower your product line with the metabolic strength of SRBio AKG.

Contact our technical team for a 50g / 500g trial sample and a complete product dossier.

• Email: admin@plantextractssr.com

• Certifications: cGMP, ISO 22000, Halal, Kosher, Vegan Verified, Non-GMO.

Shipping & Packing Information

OEM SERVICE

We offer all-inclusive product development from consultation to delivery.
We make product proposals based on the customer’s requirements, from small to large lots.

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Important B2B Disclaimer

Note to Professionals: The information provided on this website is for business-to-business (B2B) reference only and is intended for ingredient purchasers, manufacturers, and R&D professionals.

Regulatory Compliance: This product is sold as a raw material ingredient. It is not intended for direct consumer use or retail sale in its current form. It is the responsibility of the final manufacturer to ensure that any finished products containing this ingredient comply with the regulations of the country where they are marketed.

FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.