
| Chemical Name | Trimagnesium Dicitrate (Anhydrous) |
|---|---|
| CAS Number | 3344-18-1 |
| Molecular Formula | Mg₃(C₆H₅O₇)₂ |
| EINECS Number | 222-093-9 |
| Specification | 14.5% – 16.4% (Elemental Magnesium) |
| Test Method | Complexometric Titration (EDTA) for Mg; HPLC for Citrate |
| Packaging | In paper-drums with double polyethylene bags inside. Net weight: 25kg/drum |
| Main Benefits | Highly bioavailable magnesium source, supports muscle & nerve function, energy metabolism, bone health |
| Application | Dietary supplements, food & beverage fortification, pharmaceuticals, clinical nutrition |
The Gold Standard in Magnesium Bioavailability: Premium Anhydrous Magnesium Citrate by SRBio
SRBio Anhydrous Magnesium Citrate is the industry benchmark for mineral supplementation. Produced from the reaction of high-purity citric acid and magnesium carbonate, this white, odorless powder offers superior solubility and exceptional bioavailability. As the anhydrous form, it provides a higher concentration of elemental magnesium compared to its hydrated counterparts, making it the ideal choice for formulators seeking maximum efficacy in compact dosage forms like tablets and capsules.
Uncompromising Quality: SRBio’s Manufacturing Excellence
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Precision Purity & Composition Control
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Guaranteed Elemental Magnesium: Our production process is tightly controlled to ensure a consistent elemental magnesium content between 14.5% and 16.4%, allowing for precise and reliable formulation.
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High Purity Assurance: Product purity exceeds 98% as anhydrous magnesium citrate, verified by HPLC for citrate content.
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Heavy Metal Screening: ICP-MS validated limits: Arsenic (<0.5 ppm), Lead (<0.1 ppm), Cadmium (<0.05 ppm), Mercury (ND). Compliant with global pharmacopoeia (USP/EP/FCC).
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Residual Solvents: GC-FID tested; confirms absence of organic solvents, as our process is entirely water-based.
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Advanced Synthesis Technology
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Controlled Reaction & Crystallization: Our proprietary process reacts high-purity magnesium carbonate with food-grade citric acid under precisely controlled conditions. This ensures complete reaction and the formation of a consistent, high-purity anhydrous salt.
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Multi-Stage Purification: The product undergoes rigorous washing and recrystallization to eliminate any residual reactants or by-products, guaranteeing exceptional purity and a neutral taste profile.
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Low-Impact Drying: Utilizes low-temperature vacuum drying technology to remove free moisture without degrading the product or causing premature hydration. This preserves the integrity of the anhydrous form.
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Eco-Impact: Water-based synthesis with minimal waste, aligning with sustainable manufacturing principles.
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Stability & Shelf-Life Superiority
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Accelerated Stability Data: Retains ≥99% potency and shows no discoloration after 24 months at 25°C/60% RH (ICH Q1A tested) when packaged appropriately.
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Hygroscopicity Management: While magnesium citrate is known to be hygroscopic, our advanced processing and packaging minimize moisture pickup. Storage in original, tightly sealed containers is recommended.
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Light/Oxygen Protection: Nitrogen-flushed, moisture-barrier foil packaging with desiccant guarantees stability from factory to formulation.
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Scientific Evidence: Mechanism & Efficacy
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Superior Bioavailability & Absorption
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High Solubility: With solubility exceeding 180 g/L in water, it dissolves rapidly in the gastrointestinal tract, making the magnesium readily available for absorption.
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Enhanced Uptake: Clinical studies have consistently shown that organic magnesium salts like citrate offer superior bioavailability compared to inorganic forms (e.g., oxide), as they are less dependent on stomach acid for dissolution. *[Reference: Magnes Res. 2018; 31(4): 131-139]*
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Essential Physiological Roles
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Energy Metabolism: Magnesium is a critical cofactor for over 300 enzymatic reactions, including those involved in ATP (energy) production and glucose metabolism.
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Muscle & Nerve Function: It plays a vital role in regulating muscle contractions, nerve transmission, and neuromuscular excitability, helping to reduce cramps and support relaxation.
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Bone Health: Approximately 60% of the body’s magnesium is stored in bone, where it contributes to structural integrity and regulates calcium transport.
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Recognized & Recommended
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EFSA-Approved Health Claims: Recognized by the European Food Safety Authority for contributions to normal energy-yielding metabolism, muscle function, and maintenance of bones and teeth.
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Global Acceptance: Widely used in infant formula, clinical nutrition products, and weight management protocols across Europe, the Americas, and Asia.
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Formulation-Ready Advantages
| Property | SRBio Anhydrous Magnesium Citrate | Standard / Competitor |
|---|---|---|
| Appearance | Pure white, free-flowing powder | Off-white, may clump |
| Elemental Mg Content | High & Consistent (14.5-16.4%) | Lower if hydrated; variable |
| Solubility (H₂O, 25°C) | > 180 g/L (Highly soluble) | Variable |
| Bulk Density | 0.60 – 0.80 g/cm³ (optimized for tableting) | Often lower, leading to larger tablet size |
| pH (1% solution) | 5.0 – 7.0 (gentle, non-alkaline) | Can be highly variable |
| Taste | Neutral, non-metallic | May have bitter or metallic aftertaste |
Application-Specific Benefits:
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Tablets & Capsules: High bulk density and excellent compressibility allow for smaller tablet sizes with higher magnesium content per dose. Provides smooth, non-gritty disintegration.
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Powdered Beverages & Stick Packs: High solubility ensures rapid and complete dissolution, resulting in clear or slightly hazy solutions with a neutral taste.
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Functional Foods & Nutrition Bars: Stable and non-reactive; does not catalyze rancidity in fats. The neutral flavor profile does not interfere with the finished product’s taste.
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Liquid Formulations: Ideal for syrups, drops, and oral solutions due to its high solubility and stability in aqueous media.
Supply Chain & Compliance Leadership
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Audited Transparency
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Full Traceability: Batch-specific Certificates of Analysis (COA) with complete heavy metal and microbial profiles are always available.
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Production Capacity: Multiple production lines across ISO 9001 and GMP-certified facilities ensure consistent supply and scalability from R&D batches to full-scale commercial production.
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Regulatory Preparedness
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Global Compliance: Meets Food Chemicals Codex (FCC), USP/NF, and EP standards. Full documentation for GRAS determination, EU Novel Food compliance, and other regional filings available.
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Allergen Statement: Validated free from gluten, soy, dairy, nuts, and crustaceans (ELISA tested). Produced in dedicated allergen-managed facilities.
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Ethical Certifications
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Kosher & Halal Certified: Available upon request.
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Vegan & Non-GMO Verified: Sourcing and production processes ensure a final product suitable for all dietary preferences and lifestyles.
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Ecovadis Recognition: Committed to ethical labor practices and sustainable manufacturing.
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Competitive Breakdown: SRBio vs. Market Alternatives
Key Deficiencies in Standard Magnesium Citrate:
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Hydration Inconsistency: Variable water content (e.g., nonahydrate) leads to inconsistent magnesium potency and challenges in precise formulation.
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Poor Flow & Clumping: High hygroscopicity, if not managed properly, results in poor powder flow, sticking in tablet presses, and caking in bulk containers.
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Unpleasant Taste: Incomplete purification leaves a bitter or metallic aftertaste, making palatable formulations difficult.
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Low Density: Fluffy powders with low bulk density require excessively large capsule sizes, which are difficult for consumers to swallow.
SRBio’s Manufacturing Edge:
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True Anhydrous Form: Guaranteed anhydrous composition ensures maximum and consistent magnesium content, allowing for smaller, consumer-friendly dosage forms.
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Optimized Organoleptics: Rigorous washing and purification remove bitter by-products, resulting in a neutral-tasting powder ideal for high-quality supplements and foods.
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Superior Flow & Handling: Engineered particle morphology and density minimize clumping and ensure smooth, high-speed processing.
Technical Partnership Program
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Co-Development Services
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Custom Particle Engineering: We can tailor particle size distribution to your specific needs, from fine powders for suspensions to direct compression grades for tableting.
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Formulation Support: Our application lab can assist with stability studies, taste-masking strategies, and compatibility testing with other actives in your matrix.
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Market-Ready Solutions
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Custom Premixes: Combine anhydrous magnesium citrate with other vitamins, minerals, and botanicals into a homogeneous, ready-to-use premix.
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Private Label Kits: Turnkey formulas for capsules (e.g., 200mg elemental Mg), tablets, effervescent tablets, or stick packs for rapid market entry.
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Receive 1kg/5kg trial batches with COA + MSDS within 72 hours
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Xi’an SR Bio-Engineering Co., Ltd
Xi’an SRBio is a professional wholesale provider of many quality nutritional supplements products and AMINO ACID Powde etc.
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