Magnesium citrate Anhydrous-SRBio

Magnesium citrate Anhydrous

(Powder, Tablets and Capsules)

Chemical Name Trimagnesium Dicitrate (Anhydrous)
CAS Number 3344-18-1
Molecular Formula Mg₃(C₆H₅O₇)₂
EINECS Number 222-093-9
Specification 14.5% – 16.4% (Elemental Magnesium)
Test Method Complexometric Titration (EDTA) for Mg; HPLC for Citrate
Packaging In paper-drums with double polyethylene bags inside. Net weight: 25kg/drum
Main Benefits Highly bioavailable magnesium source, supports muscle & nerve function, energy metabolism, bone health
Application Dietary supplements, food & beverage fortification, pharmaceuticals, clinical nutrition

The Gold Standard in Magnesium Bioavailability: Premium Anhydrous Magnesium Citrate by SRBio

SRBio Anhydrous Magnesium Citrate is the industry benchmark for mineral supplementation. Produced from the reaction of high-purity citric acid and magnesium carbonate, this white, odorless powder offers superior solubility and exceptional bioavailability. As the anhydrous form, it provides a higher concentration of elemental magnesium compared to its hydrated counterparts, making it the ideal choice for formulators seeking maximum efficacy in compact dosage forms like tablets and capsules.

Uncompromising Quality: SRBio’s Manufacturing Excellence

  1. Precision Purity & Composition Control

    • Guaranteed Elemental Magnesium: Our production process is tightly controlled to ensure a consistent elemental magnesium content between 14.5% and 16.4%, allowing for precise and reliable formulation.

    • High Purity Assurance: Product purity exceeds 98% as anhydrous magnesium citrate, verified by HPLC for citrate content.

    • Heavy Metal Screening: ICP-MS validated limits: Arsenic (<0.5 ppm), Lead (<0.1 ppm), Cadmium (<0.05 ppm), Mercury (ND). Compliant with global pharmacopoeia (USP/EP/FCC).

    • Residual Solvents: GC-FID tested; confirms absence of organic solvents, as our process is entirely water-based.

  2. Advanced Synthesis Technology

    • Controlled Reaction & Crystallization: Our proprietary process reacts high-purity magnesium carbonate with food-grade citric acid under precisely controlled conditions. This ensures complete reaction and the formation of a consistent, high-purity anhydrous salt.

    • Multi-Stage Purification: The product undergoes rigorous washing and recrystallization to eliminate any residual reactants or by-products, guaranteeing exceptional purity and a neutral taste profile.

    • Low-Impact Drying: Utilizes low-temperature vacuum drying technology to remove free moisture without degrading the product or causing premature hydration. This preserves the integrity of the anhydrous form.

    • Eco-Impact: Water-based synthesis with minimal waste, aligning with sustainable manufacturing principles.

  3. Stability & Shelf-Life Superiority

    • Accelerated Stability Data: Retains ≥99% potency and shows no discoloration after 24 months at 25°C/60% RH (ICH Q1A tested) when packaged appropriately.

    • Hygroscopicity Management: While magnesium citrate is known to be hygroscopic, our advanced processing and packaging minimize moisture pickup. Storage in original, tightly sealed containers is recommended.

    • Light/Oxygen Protection: Nitrogen-flushed, moisture-barrier foil packaging with desiccant guarantees stability from factory to formulation.

Scientific Evidence: Mechanism & Efficacy

  1. Superior Bioavailability & Absorption

    • High Solubility: With solubility exceeding 180 g/L in water, it dissolves rapidly in the gastrointestinal tract, making the magnesium readily available for absorption.

    • Enhanced Uptake: Clinical studies have consistently shown that organic magnesium salts like citrate offer superior bioavailability compared to inorganic forms (e.g., oxide), as they are less dependent on stomach acid for dissolution. *[Reference: Magnes Res. 2018; 31(4): 131-139]*

  2. Essential Physiological Roles

    • Energy Metabolism: Magnesium is a critical cofactor for over 300 enzymatic reactions, including those involved in ATP (energy) production and glucose metabolism.

    • Muscle & Nerve Function: It plays a vital role in regulating muscle contractions, nerve transmission, and neuromuscular excitability, helping to reduce cramps and support relaxation.

    • Bone Health: Approximately 60% of the body’s magnesium is stored in bone, where it contributes to structural integrity and regulates calcium transport.

  3. Recognized & Recommended

    • EFSA-Approved Health Claims: Recognized by the European Food Safety Authority for contributions to normal energy-yielding metabolism, muscle function, and maintenance of bones and teeth.

    • Global Acceptance: Widely used in infant formula, clinical nutrition products, and weight management protocols across Europe, the Americas, and Asia.

Formulation-Ready Advantages

Property SRBio Anhydrous Magnesium Citrate Standard / Competitor
Appearance Pure white, free-flowing powder Off-white, may clump
Elemental Mg Content High & Consistent (14.5-16.4%) Lower if hydrated; variable
Solubility (H₂O, 25°C) > 180 g/L (Highly soluble) Variable
Bulk Density 0.60 – 0.80 g/cm³ (optimized for tableting) Often lower, leading to larger tablet size
pH (1% solution) 5.0 – 7.0 (gentle, non-alkaline) Can be highly variable
Taste Neutral, non-metallic May have bitter or metallic aftertaste

Application-Specific Benefits:

  • Tablets & Capsules: High bulk density and excellent compressibility allow for smaller tablet sizes with higher magnesium content per dose. Provides smooth, non-gritty disintegration.

  • Powdered Beverages & Stick Packs: High solubility ensures rapid and complete dissolution, resulting in clear or slightly hazy solutions with a neutral taste.

  • Functional Foods & Nutrition Bars: Stable and non-reactive; does not catalyze rancidity in fats. The neutral flavor profile does not interfere with the finished product’s taste.

  • Liquid Formulations: Ideal for syrups, drops, and oral solutions due to its high solubility and stability in aqueous media.

Supply Chain & Compliance Leadership

  1. Audited Transparency

    • Full Traceability: Batch-specific Certificates of Analysis (COA) with complete heavy metal and microbial profiles are always available.

    • Production Capacity: Multiple production lines across ISO 9001 and GMP-certified facilities ensure consistent supply and scalability from R&D batches to full-scale commercial production.

  2. Regulatory Preparedness

    • Global Compliance: Meets Food Chemicals Codex (FCC), USP/NF, and EP standards. Full documentation for GRAS determination, EU Novel Food compliance, and other regional filings available.

    • Allergen Statement: Validated free from gluten, soy, dairy, nuts, and crustaceans (ELISA tested). Produced in dedicated allergen-managed facilities.

  3. Ethical Certifications

    • Kosher & Halal Certified: Available upon request.

    • Vegan & Non-GMO Verified: Sourcing and production processes ensure a final product suitable for all dietary preferences and lifestyles.

    • Ecovadis Recognition: Committed to ethical labor practices and sustainable manufacturing.

Competitive Breakdown: SRBio vs. Market Alternatives

Key Deficiencies in Standard Magnesium Citrate:

  • Hydration Inconsistency: Variable water content (e.g., nonahydrate) leads to inconsistent magnesium potency and challenges in precise formulation.

  • Poor Flow & Clumping: High hygroscopicity, if not managed properly, results in poor powder flow, sticking in tablet presses, and caking in bulk containers.

  • Unpleasant Taste: Incomplete purification leaves a bitter or metallic aftertaste, making palatable formulations difficult.

  • Low Density: Fluffy powders with low bulk density require excessively large capsule sizes, which are difficult for consumers to swallow.

SRBio’s Manufacturing Edge:

  • True Anhydrous Form: Guaranteed anhydrous composition ensures maximum and consistent magnesium content, allowing for smaller, consumer-friendly dosage forms.

  • Optimized Organoleptics: Rigorous washing and purification remove bitter by-products, resulting in a neutral-tasting powder ideal for high-quality supplements and foods.

  • Superior Flow & Handling: Engineered particle morphology and density minimize clumping and ensure smooth, high-speed processing.

Technical Partnership Program

  1. Co-Development Services

    • Custom Particle Engineering: We can tailor particle size distribution to your specific needs, from fine powders for suspensions to direct compression grades for tableting.

    • Formulation Support: Our application lab can assist with stability studies, taste-masking strategies, and compatibility testing with other actives in your matrix.

  2. Market-Ready Solutions

    • Custom Premixes: Combine anhydrous magnesium citrate with other vitamins, minerals, and botanicals into a homogeneous, ready-to-use premix.

    • Private Label Kits: Turnkey formulas for capsules (e.g., 200mg elemental Mg), tablets, effervescent tablets, or stick packs for rapid market entry.

Receive 1kg/5kg trial batches with COA + MSDS within 72 hours

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