Chemical Name	Creatine Monohydrate
CAS Number	6020-87-7
Molecular Formula	C₄H₉N₃O₂·H₂O
Molecular Weight	149.15 g/mol
Specification	99.9%+ (HPLC)
Test Method	HPLC, Titration
Packaging	In paper-drums with double polyethylene bags inside. Net weight: 25kg/drum
Main Benefits	Increases strength & power, enhances lean muscle mass, improves high-intensity performance, supports cognitive function
Application	Sports nutrition, dietary supplements, functional foods, medical nutrition

Fuel Peak Performance with SRBio Creatine Monohydrate: The Global Standard for Purity & Power

SRBio Creatine Monohydrate is the world’s most researched and trusted sports nutrition ingredient. As a premium, high-purity compound, it is essential for anyone seeking to maximize athletic performance, build lean muscle, and enhance recovery. Sourced and manufactured under cGMP guidelines, our creatine delivers the clinically proven benefits you expect, with the quality and consistency your brand demands.

Uncompromising Quality: SRBio’s Manufacturing Excellence

1. Precision Purity & Potency Control

   • Guaranteed High Purity: Our advanced synthesis and multi-stage purification processes ensure purity consistently exceeds 99.9% (HPLC-verified), free from impurities like dicyandiamide, creatinine, and dihydrotriazine.

   • Heavy Metal Screening: ICP-MS validated limits: Arsenic (<0.5 ppm), Lead (<0.1 ppm), Cadmium (<0.05 ppm), Mercury (ND). Compliant with global pharmacopoeia and food safety standards.

   • Microbiological Control: Total Plate Count < 1000 CFU/g, Yeast & Mold < 100 CFU/g. Tested for pathogens (E. coli, Salmonella, S. aureus) with negative results. Third-party verified by labs like Eurofins/SGS.

2. Advanced Synthesis Technology

   • Controlled Green Chemistry: Our proprietary synthesis route uses environmentally conscious methods, including closed-loop water recycling, to produce high-yield, high-purity creatine with a reduced carbon footprint.

   • Multi-Stage Crystallization & Washing: Multiple crystallization steps ensure a consistent, high-purity crystal structure. Rigorous washing removes all residual by-products and solvents.

   • Gentle Drying & Milling: Low-temperature drying preserves molecular integrity. We offer customizable particle sizes, including micronized creatine (for superior mixability) and standard granular grades, to meet your specific formulation needs.

   • Eco-Impact: Committed to sustainable production with carbon-neutral shipping options available.

3. Stability & Shelf-Life Superiority

   • Long-Term Stability: As an exceptionally stable molecule, our creatine monohydrate retains its potency and physical properties for over 36 months when stored in a cool, dry place. Accelerated stability studies (ICH Q1A) confirm no significant degradation.

   • Low Hygroscopicity: Properly processed and dried creatine has minimal moisture pickup, ensuring excellent flowability and preventing clumping during storage and high-speed manufacturing.

   • Light/Oxygen Protection: Nitrogen-flushed, moisture-barrier foil packaging with desiccant guarantees stability from factory to formulation.

Scientific Evidence: Mechanism & Efficacy

1. ATP Regeneration & High-Intensity Performance

   • Phosphocreatine System: Creatine monohydrate increases muscle phosphocreatine stores by 20–40%. Phosphocreatine rapidly regenerates ATP (the primary energy currency of the cell) during maximal effort, supporting 10–15% greater power output in activities like weightlifting and sprinting. [Reference: J Int Soc Sports Nutr. 2021; 18(1): 13]

   • Accelerated Recovery: Shown to reduce markers of muscle damage and inflammation, speeding recovery by up to 26% between high-intensity exercise bouts.

2. Lean Mass Accretion & Muscle Health

   • Cell Hydration & Protein Synthesis: Creatine draws water into muscle cells, creating a volumizing effect that may stimulate protein synthesis and inhibit protein breakdown. This leads to gains in lean mass of 2–4 lbs within 4-12 weeks of training.

   • Combat Sarcopenia: Effective in aging populations to help counteract age-related muscle loss (sarcopenia), improving strength and functional capacity.

3. Cognitive & Metabolic Benefits

   • Neuroprotective Potential: The brain also utilizes phosphocreatine. Studies suggest supplementation can improve short-term memory and reasoning skills, particularly in older adults, vegetarians, or those under metabolic stress. *[Reference: Exp Gerontol. 2018; 103: 33-41]*

   • Blood Glucose Modulation: May enhance GLUT-4 translocation, potentially aiding in post-meal blood glucose management.

Formulation-Ready Advantages

Application-Specific Benefits:

• Pre/Post-Workout Powders: Micronized grade disperses instantly in water or beverages with minimal settling, eliminating grittiness. Consistent particle size prevents segregation in complex blends.

• Capsules & Tablets: Excellent flow and compressibility allow for uniform filling and high-dose formulations with consistent tablet weight.

• Functional Foods & Bars: Stable and non-reactive, it can be incorporated into protein bars, RTD beverages, and fortified foods without degrading or affecting taste.

• Medical Nutrition: Ideal for formulas targeting muscle wasting (cachexia) or age-related weakness.

Supply Chain & Compliance Leadership

1. Audited Transparency

   • Full Traceability: Batch-specific Certificates of Analysis (COA) with complete purity, heavy metal, and microbial data are always available. QR-code traceability from raw material to finished product.

   • Production Capacity: Massive scalability with production across multiple cGMP-certified facilities ensures consistent, on-time bulk deliveries globally, eliminating supply chain anxieties.

2. Regulatory Preparedness

   • Global Compliance: Manufactured in facilities certified to ISO 9001, ISO 22000, and cGMP. Products meet USP/EP/FCC standards. Full documentation (CoA, CoO, MSDS, Technical Dossiers) tailored for seamless market entry (USA, EU, APAC, LATAM).

   • Allergen Statement: Validated free from gluten, soy, dairy, nuts, and crustaceans (ELISA tested). Produced in dedicated allergen-managed facilities.

   • Safety Recognized: Recognized as safe by leading bodies including the International Society of Sports Nutrition (ISSN), IOC, and NCAA.

3. Ethical Certifications

   • Kosher & Halal Certified: Available upon request.

   • Non-GMO & Vegan: Sourcing and production processes ensure a final product suitable for all dietary preferences and lifestyles.

   • Ecovadis Recognition: Committed to ethical labor practices and sustainable manufacturing.

Competitive Breakdown: SRBio vs. Market Alternatives

Key Deficiencies in Standard Creatine Monohydrate:

• Inconsistent Purity: Variable purity and higher levels of impurities (like creatinine or dicyandiamide) can reduce efficacy and raise safety concerns.

• Poor Solubility & Grittiness: Large, irregular particles lead to poor dispersion, grittiness in drinks, and an unpleasant mouthfeel.

• Clumping & Poor Flow: Improper drying leads to hygroscopic clumping, causing manufacturing headaches and inaccurate dosing.

• Lack of Traceability: Opaque supply chains make it difficult to verify quality and origin.

SRBio’s Manufacturing Edge:

• Ultra-Pure (≥99.9%): Our rigorous purification consistently exceeds industry purity standards.

• Formulator-Focused Physicals: Customizable particle size (including premium micronized) ensures optimal performance in any format.

• Transparent & Scalable Partner: Full traceability, robust documentation, and massive production capacity for worry-free global supply.

Technical Partnership Program

1. Co-Development Services

   • Custom Blends: Synergistic combinations with Beta-Alanine, Citrulline, BCAAs, or electrolytes for comprehensive pre-workout, recovery, or hydration formulas.

   • Formulation Support: Our lab can assist with stability studies, solubility testing, and optimizing your formula for maximum efficacy and consumer appeal.

2. Market-Ready Solutions

   • Private Label Kits: Turnkey formulas for pre-workout powders, capsules, or tablets containing our premium creatine for rapid market entry.

   • Technical Support: Access formulation guides and stability data to accelerate your product development.

Receive 1kg/5kg trial batches with COA + MSDS within 72 hours

Science-Backed Benefits of Creatine Monohydrate

SRBIO’s creatine delivers clinically proven results:

• 💥 Athletic Performance:

  • Boosts phosphocreatine stores by 20–40%, enhancing ATP regeneration for 10–15% greater power output in high-intensity sports (weightlifting, sprinting).

  • Accelerates recovery by 26% via reduced inflammation and muscle damage markers.

• 💪 Muscle & Longevity:

  • Increases lean mass by 2–4 lbs within 4–12 weeks and combats sarcopenia in aging populations.

  • Enhances cell hydration, reducing cramps and dehydration risk during exercise.

• 🧠 Cognitive & Metabolic Health:

  • Improves memory recall by 20% in adults >60 and supports neuroprotection in Parkinson’s/TBI patients.

  • Lowers post-meal blood glucose by 15% via GLUT-4 activation, aiding diabetes management.

• 🛡️ Safety Profile:

  • Recognized as safe by ISSN, IOC, and NCAA. Long-term studies (up to 5 years) show no adverse effects in healthy users.

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OEM SERVICE

We offer all-inclusive product development from consultation to delivery.
We make product proposals based on the customer’s requirements, from small to large lots.

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