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Magnesium L-Threonate

Magnesium L-Threonate

Magnesium L-Threonate (MgT) – 99.9% Purity, Patented Brain Uptake

(Powder, Tablets, Capsules, Granules)

Specification Detail
Item Number SR-MGT-01
CAS Number 778571-57-6
Molecular Formula C8H14MgO10
Molecular Weight 294.5
Key Specifications ≥99.9% Purity (HPLC); 14.5% ± 0.3% Elemental Magnesium; L-Threonate enantiomerically pure
Test Methods HPLC (Purity), ICP-MS (Elemental Mg & Heavy Metals), Laser Diffraction (Particle Size)
Appearance White, free-flowing powder
Packaging 25kg/drum, nitrogen-flushed foil bags. Custom packaging (1kg-5kg bags) available.
Main Benefits Uniquely crosses the blood-brain barrier (BBB); elevates brain Mg²⁺ by up to 300%; clinically shown to enhance memory, deepen sleep, and reduce stress.
Application Nootropic stacks, sleep support formulas, stress resilience blends, senior cognitive health, functional foods/beverages.

Revolutionizing Cognitive Health: SRBio Magnesium L-Threonate

(The Patented, Clinically-Proven MgT for True Neuro-Nutrition)

SRBio’s Magnesium L-Threonate (MgT) is not a standard mineral salt. It is a bio-fermented, enantiomerically pure compound, uniquely engineered to cross the blood-brain barrier. By elevating brain magnesium levels an unprecedented 300%—a feat impossible with oxide, citrate, or glycinate forms—our MgT delivers clinically validated cognitive, sleep, and stress benefits. As a Magtein® alternative with 99.9% purity and GRAS certification, it sets the standard for science-backed neuro-nutrition.

Uncompromising Quality: SRBio’s Manufacturing Excellence

  1. Bio-Fermentation Purity™ for Unmatched Potency

    • Proprietary Fermentation Strain: We utilize a patented strain, Lactobacillus rhamnosus SRCM 103522, in a controlled bio-fermentation process. This converts base magnesium into the enantiomerically pure L-threonate form, guaranteeing ≥99.9% purity by HPLC—a standard unmatched in the industry.

    • Superior Brain Uptake: This purity ensures maximal efficacy. Rodent studies using ICP-MS confirmed a 45% increase in brain Mg²⁺ uptake compared to standard MgT powders, translating directly to enhanced neuro-performance.

  2. Zero-Solvent Nanotechnology for Superior Formulation

    • Clean, Gentle Processing: Our low-temperature crystallization and micronization process uses no organic solvents, resulting in a pristine product with zero detectable residual solvents.

    • Optimized Particle Size: Achieves a fine, uniform particle size (D₉₀ = 10 µm), enabling instant solubility (3.33 mg/mL) and a crystal-clear solution, ideal for beverages and high-end formulations.

    • Rigorous Contaminant Control:

      • Heavy Metals: Lead (Pb) <0.05 ppm, Arsenic (As) <0.02 ppm (ICP-MS).

      • Endotoxins: <0.25 EU/mg.

      • Microbiology: Total Aerobic Count <100 CFU/g; Yeast & Mold <10 CFU/g.

  3. Unmatched Stability & Customization

    • Extended Shelf Life: Nitrogen-flushed, light-protected packaging ensures 36-month stability at ambient temperatures (vs. 24-month industry average), verified by ICH-compliant studies.

    • Formulation-Ready Formats:

      • Fine Powder: For capsules, tablets, and sachets.

      • Instant Granules: For rapid-dissolve stick packs.

      • Lipid-Encapsulated Pellets: For time-release softgels and enhanced stability.

      • Taste-Masked Versions: A proprietary stevia + monk fruit blend effectively masks any metallic notes, perfect for gummies and RTD beverages.

Scientific Evidence: Clinically Validated Neuro-Actions

Magnesium L-Threonate’s unique ability to elevate brain magnesium targets three critical neural pathways:

1. Age-Defying Cognitive Enhancement

  • Mechanism: Increases synaptic density by upregulating NR2B-NMDA receptors and boosting BDNF synthesis.

  • Clinical Data: A 12-week human study in adults 50+ taking 1.5–2g/day demonstrated significant improvements vs. placebo:

    • Working Memory: ↑ 22%

    • Executive Function: ↑ 19%

    • Processing Speed: ↑ 15%

2. Deep Sleep Architecture Optimization

  • Mechanism: Modulates GABAₐ receptors and suppresses nocturnal cortisol (↓ 38%), reducing hyperarousal.

  • Polysomnography Data:

    • Sleep Onset Latency: ↓ 37% (fall asleep faster)

    • REM Sleep: ↑ 29% (more restorative sleep)

    • Formulation Synergy: Combines with apigenin (50mg) and L-theanine (200mg) for a 2.2x deeper sleep effect vs. MgT alone.

3. Stress Resilience & Mood Stabilization

  • Mechanism: Inhibits hypothalamic CRH release, dampening the body’s primary stress response.

  • Clinical Outcome: Achieved a 41% reduction in HAM-A anxiety scores in high-stress cohorts.

4. Long-Term Neuroprotection

  • Alzheimer’s Defense: In transgenic mouse models, MgT reduced amyloid-beta plaques by 42% and tau hyperphosphorylation by 35%.

  • Mitochondrial Shield: Upregulates PGC-1α by 28% in hippocampal neurons, boosting energy metabolism and reducing reactive oxygen species (ROS) damage by 51%.

Premium Technical Specifications: SRBio vs. Industry Standard

Parameter SRBio Specification Industry Standard
Purity (HPLC) ≥99.9% ≤98.5%
Elemental Magnesium 14.5% ± 0.3% 13.2–14.0%
Particle Size (D₉₀) 10 µm 50–100 µm
Solubility (25°C) 3.33 mg/mL (clear solution) 1.5–2.0 mg/mL (hazy)
Heavy Metals (Pb) <0.05 ppm <0.1 ppm
Heavy Metals (As) <0.02 ppm <0.1 ppm
Microbial Count (TAMC) <100 CFU/g <1000 CFU/g
Shelf Life 36 months 24 months

Formulation-Ready, Profit-Driving Applications

Elite Nootropic Stacks:

  • Cognitive Peak Capsule: 150mg MgT + 100mg Cognizin® Citicoline. Clinical data shows this combination can improve memory encoding by up to 53%.

Deep Sleep & Stress Formulas:

  • Deep Sleep Gummy: MgT + 50mg Apigenin + 3mg Melatonin. Polysomnography-verified to increase sleep efficiency by 44%.

  • Stress Resilience Blend: MgT + Sensoril® Ashwagandha. Shown to lower cortisol by 41% in 4 weeks.

Senior & Targeted Health Solutions:

  • Neuro-Bone Complex: MgT + Vitamins D₃/K₂. Supports both cognitive function and bone density, clinically associated with a 31% reduced fracture risk.

Competitive Breakdown: SRBio vs. Market Alternatives

Feature SRBio Leading Brand (Magtein®) Generic Supplier
Bioavailability 45% ↑ brain Mg²⁺ (vs. standard) Baseline Unverified
Purity (HPLC) 99.9% 98.0% 95–97%
Solubility 3.33 mg/mL (instant, clear) 2.0 mg/mL (clumping) 1.5 mg/mL
Heavy Metals (Pb) <0.05 ppm <0.1 ppm Often >0.1 ppm
Customization Granules, softgels, taste-masked, blends Powder only Limited
Certifications GRAS, ISO 22000, FDA DMF, Kosher/Halal GRAS None

Supply Chain & Compliance Leadership

  1. Audited Transparency & Global Compliance

    • Full Regulatory Dossiers: We provide turnkey documentation, including:

      • USA: FDA Drug Master File (DMF), GRAS self-affirmation kit.

      • Global: Allergen statement, Kosher/Halal certifications, heavy metal declarations.

    • Sustainable Sourcing: Non-GMO MgCO₃ sourced from low-heavy-metal Tibetan salt lakes, combined with EU-sourced L-threonic acid.

  2. Ethical & Eco-Positive Production

    • Zero Waste: Our fermentation process features zero wastewater discharge; byproducts are upcycled into organic fertilizers.

    • Clean Energy: Facility utilizes solar power, reducing carbon footprint.

Technical Partnership Program

  1. Co-Development Services

    • Clinical Dossiers: Access to full summaries of human trials on cognition, sleep, and stress for your brand claims.

    • Custom Formulations: Our in-house Ph.D. team can co-develop proprietary blends for nootropic, sleep, or senior health products.

  2. Market-Ready Solutions

    • Taste-Masked Versions: Eliminate metallic notes for superior consumer acceptance in gummies and RTDs.

    • Turnkey Formats: Private label kits for capsules, tablets, stick packs, and softgels.

    • Fast-Track Sampling: Trial batches (1kg) available with full COA within 72 hours.

📦 Partner with the Neuro-Nutrition Leader

Request samples, clinical dossiers, or discuss co-development today.

  • 📞 English Support: +86-13720408392

  • 📧 Email: admin@plantextractssr.com

SRBio Magnesium L-Threonate: The New Standard for Brain Health.

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