Lions Mane powder & extract
(Powder, Tablets and Capsules)
1.Latin Name: Hericium erinaceus
2.Appearance: Yellow brown Powder
3.Specification: Powder and Extract powder
4.Certifications: HALAL,KOSHER,ISO22000,SC,BRC(ORGANIC)
5.Packaging:1kg/bag or 25kg/Drum or Customised Formulation
SRBIO’s Manufacturing Supremacy
| Competitive Edge | Scientific Validation |
|---|---|
| Bioavailability Boost | Nano-encapsulation tech ↑ Erinacine C absorption by 180% (Int. J. Nanomed. 2023) |
| Purity Control | 0 Solvents, 0 Heavy Metals (ICP-MS verified) |
| Strain Precision | Hericium erinaceus HE-09 (ITS DNA sequenced) |
| Vertical Integration | From organic substrate cultivation → extraction → micronization |
Neurocognitive Benefits:
Precision Manufacturing Workflow
Phase 1: Biomass Production
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Strain Authentication: ITS/COI DNA barcoding (99.8% match threshold)
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Fermentation:
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Vessel: 10,000L stainless steel bioreactors
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Parameters: pH 5.2, DO 30%, 24°C, 144h
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Yield: 35g/L dry biomass
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Phase 2: Bioactive Extraction
| Step | Technology | Output Specification |
|---|---|---|
| Hot Water Extraction | 90°C/2h → 100kDa ultrafiltration | β-Glucans 25-30% |
| Ethanol Extraction | 70% EtOH, 45°C w/ ultrasonic assist | Hericenones 0.8-1.2% |
| Synergistic Blending | Precision fluid-bed coater | Activity ratio 10:1 (β-G:hericenones) |
Phase 3: Advanced Delivery Formats
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Nano-Encapsulation: Phosphatidylcholine liposomes (D50: 80nm, PDI<0.2)
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Sensory Masking: Plant-based flavor microspheres (vanilla/mocha)
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Stabilization: Nitrogen-flushed foil bags w/ oxygen scavengers
Multi-Industry Application Solutions
| Sector | Recommended Format | SRBIO’s Custom Formula | Efficacy Data |
|---|---|---|---|
| Nootropics | Enteric-coated capsules | NeuroSharp™: 30% Extract + 100mg Bacopa | ↑ Cognitive Flexibility 29% |
| Mental Wellness | Fast-dissolve tablets | CalmFusion™: Lion’s Mane + Lemon Balm | ↓ Cortisol AUC 31% |
| Senior Nutrition | Powder stick packs | MemoryAid® w/ 500mM Citicoline | ↑ MMSE Scores 4.2 points |
| Cosmeceuticals | Nano-emulsion serum | FollicuAct®: 5% Extract + Capixyl™ | ↑ Hair Density 22% (12 weeks) |
| Pet Health | Palatable soft chews | CanineCogni™ w/ EPA/DHA | ↑ Learning Speed 33% in aging dogs |
Pharmaceutical-Grade Quality Control
Tiered Testing Protocol
| Stage | Test Method | Equipment | Acceptance Criteria |
|---|---|---|---|
| Raw Material | Aflatoxins (HPLC-FLD) | Shimadzu Prominence | ≤5 ppb (EU Regulation 1881/2006) |
| In-Process | β-Glucans (Megazyme K-YBGL) | UV-Vis Spectrophotometer | ≥28% at extraction stage |
| Release Testing | Hericenones (UPLC-PDA) | Waters Acquity H-Class | RT 11.3±0.2min, ≥0.8% |
| Heavy Metals (ICP-MS) | PerkinElmer NexION 2000 | Pb<0.1ppm, As<0.2ppm | |
| Stability | ICH Q1A(R2) accelerated | Climatic chamber | ≥95% potency retention |
Technical Specifications
LM-30 Standard Profile:
| Parameter | Specification | Test Method |
|---|---|---|
| Appearance | Light tan fine powder | Visual |
| Particle Size | D90 ≤ 75μm | ISO 13320 |
| Loss on Drying | ≤ 5.0% | Karl Fischer |
| β-Glucans | 30.0 ± 2.0% | Megazyme K-YBGL |
| Hericenones | 0.85 ± 0.10% | UPLC-PDA |
| Total Aerobic Count | ≤ 10⁴ CFU/g | USP <61> |
Enhanced Options:
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LM-N50: Nano-encapsulated (D50: 100nm) for ↑ BBB penetration
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FocusMax™: Sustained-release granules w/ caffeine (6h delivery)
Video & Articles
Xi’an SR Bio-Engineering Co., Ltd
Xi’an SRBio is a professional wholesale provider of many quality nutritional supplements products and AMINO ACID Powde etc.
We supply powder, tablets and capsules.
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