| Parameter | Specification |
|---|---|
| Chemical Name | Ascorbic Acid (Vitamin C) |
| CAS Number | 50-81-7 |
| Specification | ≥98% (HPLC), Liposome encapsulation efficiency ≥85% |
| Test Method | HPLC-UV, Dynamic Light Scattering (DLS), TEM |
| Packaging | Nitrogen-flushed glass vials (liquid) / double foil bags (powder), 100g – 25kg options |
| Key Benefits | Superior bioavailability, immune system support, enhanced collagen synthesis, potent antioxidant protection, non‑acidic gastric tolerance |
| Application | Oral liquid supplements, softgels, functional beverages, topical serums, gummies, immune health formulas |
Unlock Superior Absorption with SRBio Liposomal Vitamin C
SRBio Liposomal Vitamin C represents a paradigm shift in ascorbic acid supplementation. Traditional oral Vitamin C suffers from poor bioavailability, limited by saturable intestinal transporters and rapid renal excretion. Our advanced liposomal encapsulation technology envelops Vitamin C in a phospholipid bilayer, enabling direct absorption through the intestinal lymphatic system and passive diffusion into cells. This results in significantly higher plasma and tissue levels, longer retention, and a non‑acidic, gut‑friendly profile. Produced under cGMP standards with ≥98% purity and >85% encapsulation efficiency, our Liposomal Vitamin C delivers the true potential of this essential nutrient for immune health, collagen formation, and antioxidant defense.
Uncompromising Quality: SRBio’s Liposomal Manufacturing Excellence
1. Precision Quality Control
| Parameter | SRBio Standard | Competitor Average | Test Method |
|---|---|---|---|
| Ascorbic Acid Purity (HPLC) | ≥98.0% | 95.0% – 97.0% | HPLC-UV |
| Encapsulation Efficiency | ≥85% | 50% – 70% | Size Exclusion Chromatography |
| Particle Size (Z‑Average) | 100 – 150 nm | 200 – 400 nm | DLS (Malvern) |
| Polydispersity Index (PDI) | ≤0.2 | >0.3 | DLS |
| Phospholipid Source | Non‑GMO Sunflower Lecithin | Soy or Synthetic | LC-MS |
| Heavy Metals (Pb, As) | <0.1 ppm | ≤1.0 ppm | ICP-MS |
| Residual Solvents | ND | ≤500 ppm | GC-FID |
| pH (Liquid Dispersion) | 6.0 – 7.0 (non‑acidic) | 3.5 – 4.5 | pH Meter |
2. Advanced Liposomal Technology
Our proprietary liposomal platform ensures exceptional stability, high payload, and a non‑irritating formulation.
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Proprietary Microfluidization Process: High‑pressure homogenization (up to 25,000 psi) produces unilamellar liposomes with uniform size distribution (PDI ≤0.2) and maximum encapsulation efficiency, outperforming conventional ethanol injection or thin‑film methods.
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Stabilization Technology:
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Neutral pH Buffering: Maintains formulation at pH 6.0–7.0, eliminating the gastric irritation commonly associated with ascorbic acid.
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Cryoprotectant System: Trehalose and sucrose‑based matrix prevents liposome aggregation and leakage during lyophilization (for powder format), ensuring >90% encapsulation retention after reconstitution.
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Nitrogen‑Flushed Packaging: Eliminates oxidative degradation of both Vitamin C and phospholipids, preserving potency and appearance.
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Sustainable & Clean‑Label Production:
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Solvent‑free manufacturing (no chloroform, methanol, or dichloromethane).
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Non‑GMO sunflower phospholipids—ideal for vegan and allergen‑free labels.
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100% biodegradable ingredients with minimal environmental footprint.
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3. Stability & Shelf‑Life Superiority
| Parameter | SRBio Liposomal Vitamin C | Conventional Vitamin C (Powder) |
|---|---|---|
| Stability (25°C / 60% RH) | ≥95% potency at 24 months | Degrades by 20–30% at 12 months |
| Gastric pH Resistance | Protected; <5% degradation in simulated gastric fluid (2h) | >60% degradation or oxidation |
| Storage | Room temperature (liquid stable for 18 months) | Requires cool, dry, dark conditions; prone to discoloration |
Scientific Evidence: Mechanism & Clinical Efficacy
1. Superior Bioavailability
Mechanism: Liposomal encapsulation protects Vitamin C from degradation in the gastrointestinal tract and bypasses the saturable sodium‑dependent vitamin C transporters (SVCTs). Liposomes are absorbed via intestinal lymphatic transport and direct cellular uptake.
Clinical Outcomes:
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↑3.5× higher plasma Vitamin C levels compared to non‑liposomal Vitamin C (1,000 mg dose) in a human pharmacokinetic study (SRBio in‑house, n=12).
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Achieves peak plasma concentration within 2–4 hours with sustained elevation for 12+ hours, avoiding the sharp spike and rapid excretion of standard ascorbic acid.
2. Immune Function Enhancement
Mechanism: Vitamin C accumulates in immune cells (neutrophils, lymphocytes) where it supports chemotaxis, phagocytosis, and oxidative killing. It also modulates cytokine production and shortens the duration of infections.
Clinical Outcomes:
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↓33% reduction in the duration of common cold symptoms in subjects supplemented with liposomal Vitamin C (2,000 mg/day) compared to standard Vitamin C (Journal of Clinical Immunology, 2024).
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↑25% increase in natural killer (NK) cell activity after 4 weeks of supplementation.
3. Collagen Synthesis & Skin Health
Mechanism: Vitamin C is an essential cofactor for prolyl and lysyl hydroxylases, enzymes that stabilize and cross‑link collagen. Liposomal delivery ensures higher dermal concentrations for structural support.
Clinical Outcomes:
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↑42% increase in skin collagen density measured by ultrasound after 12 weeks of daily liposomal Vitamin C (Dermatology Research & Practice, 2025).
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Significant reduction in facial fine lines and transepidermal water loss in a double‑blind placebo‑controlled study.
4. Potent Antioxidant Protection
Mechanism: Vitamin C directly scavenges reactive oxygen species (ROS) and regenerates other antioxidants such as Vitamin E and glutathione. Liposomal delivery enhances intracellular antioxidant capacity.
Clinical Outcomes:
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↓38% reduction in plasma oxidative stress markers (malondialdehyde) after 8 weeks.
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Protects endothelial function; improves flow‑mediated dilation by 18% in individuals with oxidative stress (Free Radical Biology & Medicine, 2024).
Formulation‑Ready Advantages
| Property | SRBio Liposomal Vitamin C (Liquid) | Liposomal Vitamin C (Powder) | Conventional Vitamin C |
|---|---|---|---|
| Format | Ready‑to‑use dispersion | Lyophilized, free‑flowing powder | Crystalline or powdered ascorbic acid |
| Encapsulation Efficiency | 85–92% | >85% after reconstitution | N/A |
| Organoleptic | Mild phospholipid taste; no sourness | Easily masked | Strong acidic, sour taste |
| pH | 6.0–7.0 (non‑acidic, tooth‑friendly) | Neutral upon reconstitution | pH 2.5–3.5 |
| Compatibility | Can be blended with water, juices, RTD beverages, or softgel fill | Suitable for stick packs, capsules, or reconstitution | Limited by acidity; causes protein denaturation |
Application‑Specific Benefits:
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Ready‑to‑Drink Beverages: Stable in low‑pH (3.0–5.0) formulations; no sedimentation or degradation for 18 months.
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Softgels & Capsules: High payload (up to 500 mg Vitamin C per softgel) with superior bioavailability.
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Gummies & Chewables: Zero acidic taste; non‑gritty texture; compatible with gelatin and pectin matrices.
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Topical Serums: Small particle size (<150 nm) ensures deep dermal penetration; non‑irritating formula suitable for sensitive skin.
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Injectables & IV Drips: Sterile, endotoxin‑tested (<0.5 EU/mL) liquid liposomes for clinical use.
Supply Chain & Compliance Leadership
1. Audited Transparency & Traceability
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Blockchain Traceability: Batch‑specific COA and manufacturing records accessible via QR code.
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Dual‑Sourcing Strategy: Production across ISO 14644‑1 Class 7 cleanrooms in China and the EU ensures supply security.
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Global Stock Hubs: Pre‑positioned inventory in US, EU, and Asia for rapid fulfillment.
2. Global Regulatory Certifications
| Certification / Compliance | Status / ID |
|---|---|
| cGMP (FDA‑registered facility) | Fully compliant |
| ISO 22000 / HACCP | Certified |
| Halal & Kosher | Certified |
| Vegan Society Verified | No animal‑derived ingredients |
| Non‑GMO Project Verified | Sunflower lecithin |
| Allergen Statement | Soy‑free, gluten‑free, dairy‑free |
| Endotoxin Tested | <0.5 EU/mL (injectable grade) |
3. Supply Chain Resilience
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Risk Mitigation: Redundant manufacturing lines and multiple warehousing sites prevent disruptions.
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Rapid Fulfillment: Samples shipped within 48 hours; bulk orders with expedited logistics available.
Competitive Breakdown: SRBio vs. Market Alternatives
| Capability | SRBio Liposomal Vitamin C | Standard Vitamin C (Powder/Tablets) | Generic Liposomal Vitamin C |
|---|---|---|---|
| Encapsulation Efficiency | ≥85% | N/A | 50–70% |
| Particle Size (PDI) | 100–150 nm (≤0.2) | N/A | 200–400 nm (>0.3) |
| pH | 6.0–7.0 (non‑acidic) | 2.5–3.5 | 4.0–5.5 |
| Stability (24 months) | ≥95% | <80% | <80% |
| Gastric Tolerance | Excellent (no irritation) | Frequent discomfort | Moderate |
| Bioavailability (vs. standard) | 3.5× higher | Baseline | 2.0× higher |
| Phospholipid Source | Non‑GMO Sunflower | N/A | Soy (often GMO) |
| Solvent‑Free Process | Yes | Yes | Often uses organic solvents |
Partner Success Stories
Leading US Integrative Medicine Clinic:
“We recommend SRBio Liposomal Vitamin C to patients who cannot tolerate high‑dose oral ascorbic acid due to GI sensitivity. The neutral pH and superior absorption have made it a cornerstone in our immune support protocols. Patients report fewer infections and faster recovery.”
— Clinical Director
European Skincare Brand:
“We formulated a topical serum with SRBio’s Liposomal Vitamin C. The stability at neutral pH and the ultra‑small particle size allow for a non‑stinging, highly effective product. Clinical testing showed visible improvement in skin radiance and firmness within 4 weeks.”
— R&D Manager
Technical Partnership Program
1. Co‑Development Services
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Stability Studies: ICH‑guided protocols for your specific formulation (beverages, softgels, topicals, gummies).
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Custom Formulations:
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Immune Shield™: Liposomal Vitamin C + Liposomal Zinc + Vitamin D3 for synergistic immune support.
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Collagen Activator: Liposomal Vitamin C + Hydrolyzed Collagen Peptides + Hyaluronic Acid.
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Antioxidant Complex: Liposomal Vitamin C + Liposomal Glutathione + Alpha‑Lipoic Acid.
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Bioavailability Testing: Caco‑2 cell assays and human pilot PK studies available.
2. Market‑Ready Solutions
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Private Label Kits: Turnkey liquid vials, softgels, stick packs, or gummies with full regulatory dossiers.
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Custom Packaging: Amber glass vials with child‑resistant caps, nitrogen‑flushed stick packs, or branded bulk containers.
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Regulatory Support: Full documentation for GRAS, Novel Food (EU), NDI (US), and clinical trial applications.
3. Rapid Sampling
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Receive 50 g / 100 g lyophilized powder with full COA, stability summary, and MSDS within 72 hours.
Partner with SRBio for Advanced Liposomal Vitamin C
Ready to formulate with the most stable, bioavailable, and gut‑friendly Liposomal Vitamin C on the market? Request custom samples, clinical dossiers, or discuss co‑branded formulations.
📧 Email: admin@plantextractssr.com
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OEM SERVICE
We offer all-inclusive product development from consultation to delivery.
We make product proposals based on the customer’s requirements, from small to large lots.
